Celiac Disease Resolution After Allogeneic Bone Marrow Transplantation is Associated with Absence of Gliadin-Specific Memory Response by Donor-Derived Intestinal T-cells

被引:0
作者
Shomron Ben-Horin
Sylvie Polak-Charcon
Iris Barshack
Orit Picard
Ella Fudim
Miri Yavzori
Camila Avivi
Corine Mardoukh
Avichai Shimoni
Yehuda Chowers
Yaakov Maor
机构
[1] Tel-Aviv University,Department of Gastroenterology, Chaim Sheba Medical Center
[2] Tel-Aviv University,Department of Pathology, Chaim Sheba Medical Center
[3] Tel-Aviv University,Hematology Department, Chaim Sheba Medical Center
来源
Journal of Clinical Immunology | 2013年 / 33卷
关键词
Celiac disease; gliadin; gluten-specific CD4+ T-cells; T-cell memory response; bone marrow transplantation;
D O I
暂无
中图分类号
学科分类号
摘要
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页码:1395 / 1402
页数:7
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[1]  
Green PH(2003)Coeliac disease Lancet 362 383-391
[2]  
Jabri B(2003)Association between innate response to gliadin and activation of pathogenic T cells in coeliac disease Lancet 362 30-37
[3]  
Maiuri L(2004)A direct role for NKG2D/MICA interaction in villous atrophy during celiac disease Immunity 21 367-377
[4]  
Ciacci C(2006)Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease Gut 55 469-477
[5]  
Ricciardelli I(2004)Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease Immunity 21 357-366
[6]  
Hue S(2007)Celiac disease: pathogenesis of a model immunogenetic disease J Clin Invest 117 41-49
[7]  
Mention JJ(2003)Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease Gastroenterology 125 730-745
[8]  
Monteiro RC(2008)Transepithelial transport and enzymatic detoxification of gluten in gluten-sensitive rhesus macaques PLoS ONE 3 e1857-10054
[9]  
Di Sabatino A(1998)Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin Proc Natl Acad Sci 95 10050-685
[10]  
Ciccocioppo R(2006)Characterizing the circulating, gliadin-specific CD4+ memory T cells in patients with celiac disease: linkage between memory function, gut homing and Th1 polarization J Leukoc Biol 79 676-919