Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice

[1] Lebwohl D(1998)Clinical development of platinum complexes in cancer therapy: an historical perspective and an update Eur J Cancer 34 1522-1534

[2] Canetta R(1994)Comparative nephrotoxicity of a novel platinum compound, cisplatin, and carboplatin in male Wistar rats Fundam Appl Toxicol 22 73-79

[3] Wolfgang GH(1994)Cisplatin generates superoxide anion by interaction with DNA in a cell-free system Biochem Biophys Res Commun 203 1175-1180

[4] Dominick MA(1997)Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain J Pharmacol Exp Ther 280 638-649

[5] Walsh KM(1998)In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity Kidney Int 53 394-401

[6] Hoeschele JD(1993)Role of mitochondria in cisplatin-induced oxidative damage exhibited by rat renal cortical slices Biochem Pharmacol 45 2215-2222

[7] Pegg DG(2002)Changes in glutathione-related enzymes in tumor-bearing mice after cisplatin treatment Cell Biol Toxicol 18 349-358

[8] Masuda H(1998)The role of oxygen free radicals in cisplatin-induced acute renal failure in rats J Lab Clin Med 131 518-526

[9] Tanaka T(2005)Cisplatin-associated nephrotoxicity and pathological events Contrib Nephrol 148 107-121

[10] Takahama U(2008)Cisplatin nephrotoxicity: mechanisms and renoprotective strategies Kidney Int 73 994-1007

[1] Lebwohl D(1998)Clinical development of platinum complexes in cancer therapy: an historical perspective and an update Eur J Cancer 34 1522-1534

[2] Canetta R(1994)Comparative nephrotoxicity of a novel platinum compound, cisplatin, and carboplatin in male Wistar rats Fundam Appl Toxicol 22 73-79

[3] Wolfgang GH(1994)Cisplatin generates superoxide anion by interaction with DNA in a cell-free system Biochem Biophys Res Commun 203 1175-1180

[4] Dominick MA(1997)Cisplatin-induced nephrotoxicity in porcine proximal tubular cells: mitochondrial dysfunction by inhibition of complexes I to IV of the respiratory chain J Pharmacol Exp Ther 280 638-649

[5] Walsh KM(1998)In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity Kidney Int 53 394-401

[6] Hoeschele JD(1993)Role of mitochondria in cisplatin-induced oxidative damage exhibited by rat renal cortical slices Biochem Pharmacol 45 2215-2222

[7] Pegg DG(2002)Changes in glutathione-related enzymes in tumor-bearing mice after cisplatin treatment Cell Biol Toxicol 18 349-358

[8] Masuda H(1998)The role of oxygen free radicals in cisplatin-induced acute renal failure in rats J Lab Clin Med 131 518-526

[9] Tanaka T(2005)Cisplatin-associated nephrotoxicity and pathological events Contrib Nephrol 148 107-121

[10] Takahama U(2008)Cisplatin nephrotoxicity: mechanisms and renoprotective strategies Kidney Int 73 994-1007