Optimization of alkaline protease production by Bacillus sp. using taguchi methodology

被引：0
|
作者：
R. S. Prakasham
Ch. Subba Rao
R. Sreenivas Rao
S. Rajesham
P. N. Sarma
机构：
[1] Indian Institute of Chemical Technology,Biochemical and Environmental Engineering Centre
[2] PRRM Engineering College,undefined
来源：
Applied Biochemistry and Biotechnology | 2005年 / 120卷
关键词：
Alkaline protease; sp.; production; optimization; Taguchi methodology;
D O I：
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中图分类号：
学科分类号：
摘要：
Optimization of alkaline protease production parameters by Bacillus sp. was investigated using Taguchi methodology. The pH of the medium was observed to be the most significant factor among all selected optimization parameters at an individual level. The combinatorial influence of least significant factors, inoculum level and salt solution concentration (at the individual level), resulted in an interacting severity index of 76%, suggesting their interactive role in the regulation of protease production in this microbial species. Protease production could be improved more than 100% with Taguchi’s optimized conditions of the medium composition by this microorganism.
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页码：133 / 144
页数：11
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