The impact of negative selection on thymocyte migration in the medulla

被引：0
作者：
Marie Le Borgne
Ena Ladi
Ivan Dzhagalov
Paul Herzmark
Ying Fang Liao
Arup K Chakraborty
Ellen A Robey
机构：
[1] University of California,Division of Immunology, Department of Molecular and Cell Biology
[2] Massachusetts Institute of Technology,Department of Chemistry, Department of Chemical Engineering and Department of Biological Engineering
[3] Present address: Department of Pathology and Immunology,undefined
[4] Washington University School of Medicine,undefined
[5] St. Louis,undefined
[6] Missouri,undefined
[7] USA.,undefined
来源：
Nature Immunology | 2009年 / 10卷
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学科分类号：
摘要：
Self-reactive thymocytes are eliminated through negative selection in the thymic medulla. Robey and colleagues find that autoreactive thymocytes show slower and more confined migration than that of polyclonal thymocytes in the medulla.
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页码：823 / 830
页数：7
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