The impact of negative selection on thymocyte migration in the medulla

[1] Kyewski B(2006)A central role for central tolerance Annu. Rev. Immunol. 24 571-606

[2] Klein L(2002)Projection of an immunological self shadow within the thymus by the aire protein Science 298 1395-1401

[3] Anderson MS(2009)Aire Annu. Rev. Immunol. 27 287-312

[4] Mathis D(2001)Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self Nat. Immunol. 2 1032-1039

[5] Benoist C(2005)The cellular mechanism of Aire control of T cell tolerance Immunity 23 227-239

[6] Derbinski J(2003)Aire regulates negative selection of organ-specific T cells Nat. Immunol. 4 350-354

[7] Schulte A(2004)Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation J. Exp. Med. 200 1039-1049

[8] Kyewski B(2006)Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus Nat. Immunol. 7 1092-1100

[9] Klein L(2003)Two developmentally distinct populations of dendritic cells inhabit the adult mouse thymus: demonstration by differential importation of hematogenous precursors under steady state conditions J. Immunol. 170 3514-3521

[10] Anderson MS(2007)Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire J. Exp. Med. 204 2521-2528

[1] Kyewski B(2006)A central role for central tolerance Annu. Rev. Immunol. 24 571-606

[2] Klein L(2002)Projection of an immunological self shadow within the thymus by the aire protein Science 298 1395-1401

[3] Anderson MS(2009)Aire Annu. Rev. Immunol. 27 287-312

[4] Mathis D(2001)Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self Nat. Immunol. 2 1032-1039

[5] Benoist C(2005)The cellular mechanism of Aire control of T cell tolerance Immunity 23 227-239

[6] Derbinski J(2003)Aire regulates negative selection of organ-specific T cells Nat. Immunol. 4 350-354

[7] Schulte A(2004)Central tolerance to tissue-specific antigens mediated by direct and indirect antigen presentation J. Exp. Med. 200 1039-1049

[8] Kyewski B(2006)Clonal deletion of thymocytes by circulating dendritic cells homing to the thymus Nat. Immunol. 7 1092-1100

[9] Klein L(2003)Two developmentally distinct populations of dendritic cells inhabit the adult mouse thymus: demonstration by differential importation of hematogenous precursors under steady state conditions J. Immunol. 170 3514-3521

[10] Anderson MS(2007)Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire J. Exp. Med. 204 2521-2528