Antioxidant status and peroxidative stress in mother and newborn - A pilot study

被引：15

作者：

Upadhyaya C. ^{[1
]}

Mishra S. ^{[1
]}

Singh P.P. ^{[2
]}

Sharma P. ^{[1
,3
]}

机构：

[1] Department of Biochemistry, S.M.S. Medical College, Jaipur

[2] Darshan Dental College, Udaipur

[3] Deptt. of Biochemistry, SMS Medical College

来源：

Indian Journal of Clinical Biochemistry | 2005年 / 20卷 / 1期

关键词：

Ascorbic acid; Mother; Newborn; Peroxidative stress; Retinol; α-Tocopherol; β-Carotene;

D O I：

10.1007/BF02893038

中图分类号：

学科分类号：

摘要：

Serum antioxidant status and peroxidative stress was estimated in 30 pregnant women, their newborn infants and 25 non-pregnant women. Serum Ascorbic acid, α-tocopherol, retinol & β-carotene levels were found to be significantly reduced and peroxidative stress was significantly higher in mothers as compared to matched non-pregnant women. Newborn had significantly higher levels of ascorbic acid as compared to their mother but had significantly lower levels of lipid soluble vitamins. The peroxidative stress in newborn was found to be significantly less as compared to their mothers. A positive correlation of ascorbic acid and α-tocopherol levels between mother and newborn reflects that their status in mother does influence the newborn status.

引用

页码：30 / 34

页数：4

共 18 条

[1]

Quanungo S., Mukherjea M., Ontogenic profile of some antioxidants and lipid per-oxidation in human placental and fetal tissues, Mol. Cell. Biochem., 215, 1-2, pp. 11-19, (2000)

[2]

Clapp J.F., Maternal physiological adaptation during early human pregnancy, Am. J. Obstet Gynaecol., (1988)

[3]

Pernoll M.L., Metcalfe J., Kovacl P.A., Et al., Ventilation during rest and exercise in in pregnancy & post partum, Respir. Physiol., 25, (1975)

[4]

Alaily A.B., Carral K.B., Pulmonary ventilation in pregnancy, Br. J. Obstet. Gynaecol ., 85, (1978)

[5]

Lachilli B., Hininger I., Faure H., Arnaud J., Richard M.J., Favier A., Roussel A.M., Increased lipid per-oxidation in pregnant women after Iron and vitamin C supplementation, Boil. Trace. Elem. Res., 83, 2, pp. 103-110, (2001)

[6]

Natelson S., Techniques of Clinical Chemistry, pp. 162-165, (1971)

[7]

Barker H., Frand O., Clinical Vitaminology, Methods and Interpretation, (1968)

[8]

Halliwell B., Chirico S., Lipid per-oxidation: Its mechanism, measurement and significance, Am. J. Clin. Nutr., 57, 1, (1993)

[9]

Gitto E., Reiter R.J., Karbownik M., Tan D.X., Gitto P., Barberi S., Barberi I., Causes of oxidative stress in the pre and perinatal period, Biol. Neonate, 81, 3, pp. 146-157, (2002)

[10]

John B.W., Ed., (1991)

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