Lasting neurobehavioral abnormalities in rats after neonatal activation of serotonin 1A and 1B receptors: possible mechanisms for serotonin dysfunction in autistic spectrum disorders

被引:0
作者
Nidhi Khatri
Kimberly L. Simpson
Rick C. S. Lin
Ian A. Paul
机构
[1] University of Mississippi Medical Center,Department of Pharmacology and Toxicology
[2] University of Mississippi Medical Center,Department of Neurobiology and Anatomical Sciences
[3] University of Mississippi Medical Center,Department of Psychiatry and Human Behavior
来源
Psychopharmacology | 2014年 / 231卷
关键词
Selective serotonin reuptake inhibitor; Autism; Antidepressant; Serotonin; Development; Sensory systems; Social behavior; Neonatal exposure; Citalopram; 8-OH-DPAT; CGS-12066B; WAY-100635; GR-127935;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1191 / 1200
页数:9
相关论文
共 291 条
[1]  
Aghajanian GK(1967)The formation of synaptic junctions in developing rat brain: a quantitative electron microscopic study Brain Res 6 716-727
[2]  
Bloom FE(2012)Altered cerebellar organization and function in monoamine oxidase A hypomorphic mice Neuropharmacology 63 1208-17
[3]  
Alzghoul L(1990)The hyperserotonemia of autism. Ann. N.Y Acad Sci 600 331-340
[4]  
Bortolato M(2001)Modern view on an ancient chemical: serotonin effects on proliferation, maturation, and apoptosis Brain Res Bull 56 414-424
[5]  
Delis F(1993)Serotonin 1B receptors in the developing somatosensory and visual cortices are located on thalamocortical axons Proc Natl Acad Sci U S A 90 153-157
[6]  
Thanos PK(1985)Relationship between clinical effects, serum drug concentration and serotonin uptake inhibition in depressed patients treated with citalopram. A double-blind comparison of three dose levels Eur J Clin Pharmacol 28 553-557
[7]  
Darling RD(2013)Monoamine oxidase A and A/B knockout mice display autistic-like features Int J Neupsychopharmacology 16 869-88
[8]  
Godar SC(1994)The mouse 5-hydroxytryptamine 1B receptor is localized predominantly on axon terminals Neuroscience 58 167-182
[9]  
Zhang J(1998)A critical period of brain development: studies of cerebral glucose utilization with PET Prev Med 27 184-188
[10]  
Grant S(2004)Diagnosis and treatment of depression during pregnancy CNS Spectr 9 209-216