Recombinant human activated protein C ameliorates oleic acid-induced lung injury in awake sheep

被引:0
作者
Kristine Waerhaug
Mikhail Y Kirov
Vsevolod V Kuzkov
Vladimir N Kuklin
Lars J Bjertnaes
机构
[1] University of Tromsø,Department of Anesthesiology, Institute of Clinical Medicine, Faculty of Medicine
[2] Northern State Medical University,Department of Anesthesiology
来源
Critical Care | / 12卷
关键词
Oleic Acid; Acute Lung Injury; Extravascular Lung Water; Right Atrial Pressure; Systemic Vascular Resistance Index;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 337 条
[1]  
Quinlan GJ(1996)Plasma fatty acid changes and increased lipid peroxidation in patients with adult respiratory distress syndrome Crit Care Med 24 241-246
[2]  
Lamb NJ(1984)Changes in fatty acids in phospholipids of the bronchoalveolar fluid in bacterial pneumonia and in adult respiratory distress syndrome Clin Chem 30 521-523
[3]  
Evans TW(1996)An increase in serum C18 unsaturated free fatty acids as a predictor of the development of acute respiratory distress syndrome Crit Care Med 24 1129-1136
[4]  
Gutteridge JM(1994)ARDS: clinical lessons from the oleic acid model of acute lung injury Am J Respir Crit Care Med 149 245-260
[5]  
Baughman RP(1984)Proteolytic inactivation of human factor VIII procoagulant protein by activated human protein C and its analogy with factor V Blood 63 486-489
[6]  
Stein E(1979)The inhibition of blood coagulation by activated Protein C through the selective inactivation of activated Factor V Biochim Biophys Acta 571 333-342
[7]  
MacGee J(2007)Influence of drotrecogin alpha (activated) infusion on the variation of Bax/Bcl-2 and Bax/Bcl-xl ratios in circulating mononuclear cells: a cohort study in septic shock patients Crit Care Med 35 69-75
[8]  
Rashkin M(2005)Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation Blood 105 3178-3184
[9]  
Sahebjami H(2007)Recombinant activated protein C induces dose-dependent changes in inflammatory mediators, tissue damage, and apoptosis in Surg Infect (Larchmt) 8 377-386
[10]  
Bursten SL(2000)rat model of sepsis Br J Haematol 110 130-134