Role of neuroimaging in our understanding of the pathogenesis of primary headaches

被引:5
作者
Mechtler L. [1 ]
机构
[1] Dent Headache Center, Dent Neurologic Institute, Amherst, NY 14226
关键词
Migraine; Single Photon Emission Compute Tomography; Capsaicin; Cluster Headache; Migraine Attack;
D O I
10.1007/s11916-996-0015-1
中图分类号
学科分类号
摘要
This article reviews new advances in neuroimaging of primary headaches. Imaging of the brain is reaching a new stage of maturity as the basic neural systems that participate in the pathogenesis of headaches are identified. Given the rapid advances in functional neuroimaging, it is no surprise that recent studies have supported the neurovascular theory of migraine and cluster headache. It is clear that functional neuroimaging will continue to be of paramount importance and ultimately may serve as the bridge between molecular and clinical domains in the field of headache research. Copyright © 2004 by Current Science Inc.
引用
收藏
页码:404 / 409
页数:5
相关论文
共 55 条
  • [1] Wolff H.G., Headache and Other Pain, (1963)
  • [2] Lashley K.S., Patterns of cerebral integration indicated by the scotomas of migraine, Arch. Neurol. Psychol., 46, pp. 331-339, (1941)
  • [3] Leao A.A., Spreading depression of activity in the cerebral cortex, J. Neurophysiol., 8, pp. 379-390, (1944)
  • [4] Olesen J., Larsen B., Lauritzen M., Focal hyperemia followed by spreading oligemia and impaired activation of rCBF in classic migraine, Ann. Neurol., 9, pp. 344-352, (1981)
  • [5] Lauritzen M., Pathophysiology of the migraine aura: The spreading depression theory, Brain, 117, pp. 199-210, (1994)
  • [6] Cao Y., Welch K.M., Aurora S., Vikingstad E.M., Functional MRI-BOLD of visually triggered headache in patients with migraine, Arch. Neurol., 56, pp. 548-554, (1999)
  • [7] Hadjikhani N., Sanchez del Rio M., Wu O., Mechanisms of migraine aura revealed by functional MRI in human visual cortex, Proc. Natl. Acad. Sci. U S A, 98, pp. 4687-4692, (2001)
  • [8] Sanchez del Rio M., Bakker D., Wu O., Perfusion-weighted imaging during migraine spontaneous visual aura and headache, Cephalalgia, 19, pp. 704-707, (1999)
  • [9] Cutrer F.M., Sorensen A.G., Weisskoff R.M., Perfusion-weighted imaging defects during spontaneous migrainous aura, Ann. Neurol., 43, pp. 25-31, (1998)
  • [10] Aurora S.K., Cao Y., Bowyer S.M., Et al., The occipital cortex is hyperexcitable in migraine