The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation

被引:0
|
作者
Hua-Chen Chang
Sarita Sehra
Ritobrata Goswami
Weiguo Yao
Qing Yu
Gretta L Stritesky
Rukhsana Jabeen
Carl McKinley
Ayele-Nati Ahyi
Ling Han
Evelyn T Nguyen
Michael J Robertson
Narayanan B Perumal
Robert S Tepper
Stephen L Nutt
Mark H Kaplan
机构
[1] Herman B Wells Center for Pediatric Research,Department of Pediatrics
[2] Indiana University School of Medicine,Department of Microbiology and Immunology
[3] Indiana University School of Medicine,Department of Medicine
[4] Indiana University School of Medicine,undefined
[5] School of Informatics,undefined
[6] Indiana University-Purdue University,undefined
[7] Indianapolis,undefined
[8] The Walter and Eliza Hall Institute of Medical Research,undefined
来源
Nature Immunology | 2010年 / 11卷
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学科分类号
摘要
Interleukin 9 secretion contributes to allergic inflammation. Kaplan and colleagues identify the transcription factor PU.1 as being necessary for TH9 differentiation and as a contributing factor in allergic airway inflammation.
引用
收藏
页码:527 / 534
页数:7
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