Evaluation of Antitumor Efficiency of High Intensity Radiation 169Yb Source on Experimental Sarcoma M-1

被引:0
|
作者
S. E. Ulyanenko
S. N. Koryakin
A. A. Lychagin
M. N. Kuznetsova
V. I. Potetnya
L. N. Ulyanenko
A. I. Brovin
机构
[1] Ministry of Health of the Russian Federation,A. F. Tsyb Medical Radiological Research Center, Affiliated Branch of the National Medical Research Radiological Center
来源
Bulletin of Experimental Biology and Medicine | 2019年 / 167卷
关键词
Ytterbium-169; high-dose rate brachytherapy; antitumor efficacy; sarcoma М-1;
D O I
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学科分类号
摘要
Rats with sarcoma M-1 were exposed to high dose rate irradiation with 169Yb source. In 25 days after introduction of a trocar with sealed capsule with 169Yb source into the tumor, complete tumor regression was observed in 70% animals. The results suggest feasibility of using 169Yb source for high-dose rate brachytherapy and development of the personalized medicine approaches.
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页码:84 / 86
页数:2
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