Incorporating common biomarkers into the clinical management of heart failure

被引:4
作者
Halkar M. [1 ]
Tang W.H.W. [2 ,3 ]
机构
[1] Department of Hospital Medicine, Medicine Institute, Cleveland Clinic, Cleveland, OH
[2] Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH
[3] Cleveland, OH 44195, 9500 Euclid Avenue
基金
美国国家卫生研究院;
关键词
Albuminuria; Anemia; Azotemia; Biomarker; BNP; Creatinine; Cystatin C; e GFR; ESR; Heart failure; Heart failure management; Hyponatremia; Markers; Natriuretic peptide; NGAL; NT-proBNP; Prognosis; Renal insufficiency; Sodium;
D O I
10.1007/s11897-013-0165-5
中图分类号
学科分类号
摘要
Heart failure is a prevalent and costly disease, and its management with polypharmacy is complex. Commonly available biomarkers primarily help to 1) establish or refute the diagnosis of heart failure; 2) help to determine the disease severity; and 3) identify adverse consequences of treatment. Although several of them are commonly ordered (such as electrolytes, renal and liver function), their use is primarily based on broad clinical experience rather than established evidence. The availability of cardiac-specific natriuretic peptide testing has provided an evidence-based breakthrough in our abilities to establish the diagnosis and severity of heart failure, yet the appropriate boundaries to guide management are still in refinement. © 2013 Springer Science+Business Media New York.
引用
收藏
页码:450 / 457
页数:7
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