X-ray structure of a prokaryotic pentameric ligand-gated ion channel

被引：0
|
作者：
Ricarda J. C. Hilf
Raimund Dutzler
机构：
[1] University of Zürich,Department of Biochemistry
[2] Winterthurer Strasse 190,undefined
[3] CH-8057 Zürich,undefined
[4] Switzerland,undefined
来源：
Nature | 2008年 / 452卷
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学科分类号：
摘要：
The X-ray structure of a prokaryotic pentameric ligand-gated ion channels (pLGIC) from the bacterium Erwinia chrysanthemi (ELIC) at 3.3 Å resolution is presented. This study reveals the first structure of a pLGIC at high resolution and provides an important model system for the investigation of the general mechanisms of ion permeation and gating within the family.
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页码：375 / 379
页数：4
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