E2 enzymes: lessons in ubiquitin transfer from XLID patients

被引:0
作者
Martina Foglizzo
Catherine L. Day
机构
[1] University of Otago,Department of Biochemistry, School of Biomedical Sciences
来源
Nature Chemical Biology | 2019年 / 15卷
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摘要
Characterization of a novel mutation in the E2 ubiquitin-conjugating enzyme UBE2A accounts for the decreased activity of the mutant enzyme that underlies disease and provides important insight into the catalytic mechanism of E2s.
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页码:6 / 7
页数:1
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