Non-transferrin-bound iron in plasma following administration of oral iron drugs

被引：0
作者：
Bernd Dresow
Doerte Petersen
Roland Fischer
Peter Nielsen
机构：
[1] Zentrum für Experimentelle Medizin Universitätsklinikum Hamburg-Eppendorf,Inst. für Biochemie und Molekularbiologie II: Molekulare Zellbiologie
来源：
BioMetals | 2008年 / 21卷
关键词：
Non-transferrin-bound iron—NTBI; Oral iron drugs; Transferrin saturation; Iron medication; Risk factor;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Non-transferrin-bound iron (NTBI) was detected in serum samples from volunteers with normal iron stores or from patients with iron deficiency anaemia after oral application of pharmaceutical iron preparations. Following a 100 mg ferrous iron dosage, NTBI values up to 9 μM were found within the time period of 1–4 h after administration whereas transferrin saturation was clearly below 100%. Smaller iron dosages (10 and 30 mg) gave lower but still measurable NTBI values. The physiological relevance of this finding for patients under iron medication has to be elucidated.
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页码：273 / 276
页数：3
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