Simplex Lattice Design and Machine Learning Methods for the Optimization of Novel Microemulsion Systems to Enhance p-Coumaric Acid Oral Bioavailability: In Vitro and In Vivo Studies

被引:0
作者
Nayera Nasser
Rania M. Hathout
Hend Abd-Allah
Omaima A. Sammour
机构
[1] Ain Shams University,Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy
来源
AAPS PharmSciTech | / 25卷
关键词
cytotoxicity; microemulsions; p-coumaric acid; re-dispersibility;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 296 条
[1]  
Nagai H(2017)Cancer prevention from the perspective of global cancer burden patterns J Thorac Dis. 9 448-451
[2]  
Kim YH(2020)Management of the toxicity of chemotherapy and targeted therapies in elderly cancer patients Clin Transl Oncol. 22 457-467
[3]  
Heredia JFV(2019)Fabrication, characterization, and in vitro evaluation of pegylated glyceride Labrasol® nanostructured lipid carrier composites of methotrexate: the pathway to effective cancer Therapy Asian J Pharm Clin Res. 12 229-237
[4]  
Gironés SR(2011)Nanotherapeutics to overcome conventional cancer chemotherapy limitations J Pharm Sci. 14 67-77
[5]  
Munarriz BJ(2016)Nanodrug delivery : is the enhanced permeability and retention effect sufficient for curing cancer ? Bioconjug Chem. 27 2225-2238
[6]  
Guillén JSC(2010)Bioavailability of hydroxycinnamates : a brief review of in vivo and in vitro studies Phytochem Rev J. 9 133-145
[7]  
Panda R(2018)A review of analytical methods for p-coumaric acid in plant-based products, beverages, and biological matrices Crit Rev Anal Chem. 49 21-31
[8]  
Kuotsu K(2015)p -Coumaric acid and its conjugates : dietary sources, pharmacokinetic properties and biological activities J Sci Food Agric. 96 2952-2962
[9]  
Moorthi C(2010)p-Coumaric acid-zinc basic salt nanohybrid for controlled release and sustained antioxidant activity J Phys Chem Solids. 71 647-649
[10]  
Manavalan R(2013)Biodegradable coumaric acid-based poly(anhydride-ester) synthesis and subsequent controlled release Macromol Rapid Commun. 34 1231-1236