Heterogeneity of ERG expression in prostate cancer: a large section mapping study of entire prostatectomy specimens from 125 patients

被引:0
作者
Maria-Christina Tsourlakis
Annegret Stender
Alexander Quaas
Martina Kluth
Corinna Wittmer
Alexander Haese
Markus Graefen
Stefan Steurer
Ronald Simon
Jan Korbel
Joachim Weischenfeldt
Hartwig Huland
Guido Sauter
Thorsten Schlomm
Sarah Minner
机构
[1] University Medical Center Hamburg-Eppendorf,Institute of Pathology
[2] University Medical Center Hamburg-Eppendorf,Martini
[3] Genome Biology Unit,Clinic Prostate Cancer Center
[4] European Molecular Biology Laboratory (EMBL),Department of Urology
[5] University Medical Center Hamburg-Eppendorf,undefined
来源
BMC Cancer | / 16卷
关键词
Prostate cancer; ERG; Heterogeneity;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 185 条
[1]  
Jemal A(2011)Global cancer statistics CA Cancer J Clin 61 69-90
[2]  
Bray F(2003)Treatment options for androgen-independent prostate cancer Clin Adv Hematol Oncol 1 49-57
[3]  
Center MM(2005)Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer Science 310 644-648
[4]  
Ferlay J(2010)Antibody-based detection of ERG rearrangement-positive prostate cancer Neoplasia 12 590-598
[5]  
Ward E(2011)ERG status is unrelated to PSA recurrence in radically operated prostate cancer in the absence of antihormonal therapy Clin Cancer Res 17 5878-5888
[6]  
Forman D(2009)Characterization of ERG, AR and PTEN gene status in circulating tumor cells from patients with castration-resistant prostate cancer Cancer Res 69 2912-2918
[7]  
Gulley J(2010)The ability of biomarkers to predict systemic progression in men with high-risk prostate cancer treated surgically is dependent on ERG status Cancer Res 70 8994-9002
[8]  
Figg WD(2013)Integrative genomic analyses reveal androgen-driven somatic alteration landscape in early-onset prostate cancer Cancer Cell 23 159-170
[9]  
Dahut WL(2013)Marked heterogeneity of ERG expression in large primary prostate cancers Mod Pathol 26 106-116
[10]  
Tomlins SA(2010)ERG oncoprotein expression in prostate cancer: clonal progression of ERG-positive tumor cells and potential for ERG-based stratification Prostate Cancer Prostatic Dis 13 228-237