Uveitis associated with juvenile idiopathic arthritis

Uveitis affects 11–30% of children with juvenile idiopathic arthritis (JIA)Chronic anterior uveitis is usually asymptomatic initially but can lead to visually disabling complications; therefore, screening is essentialInitial treatment is with topical corticosteroids but evidence supports the early introduction of systemic immunosuppressive drugs, such as methotrexate, as steroid-sparing agentsProspective controlled studies of biologic therapies, including adalimumab and tocilizumab, are underway or plannedFuture research to investigate the pathogenesis of JIA-associated uveitis and identify novel biomarkers could enable earlier diagnosis and more-effective treatment