Microbiome recovery in adult females with uncomplicated urinary tract infections in a randomised phase 2A trial of the novel antibiotic gepotidacin (GSK2140944)

Bax BD(2010)Type IIA topoisomerase inhibition by a new class of antibacterial agents Nature. 466 935-940

Chan PF(2016)Clostridium difficile colitis: pathogenesis and host defence Nat Rev Microbiol 14 609-620

Eggleston DS(2010)Association between the use of antibiotics in the first year of life and pediatric inflammatory bowel disease Am J Gastroenterol 105 2687-2692

Fosberry A(2019)Association between antibiotics in the first year of life and celiac disease Gastroenterology. 156 2217-2229

Gentry DR(2018)Extensive impact of non-antibiotic drugs on human gut bacteria Nature. 555 623-628

Gorrec F(2016)Alekseyenko a v., Gao Z, et al. effect of antibiotic pre-treatment and pathogen challenge on the intestinal microbiota in mice Gut Pathogens 8 1-10

Giordano I(2015)Microbiome changes in healthy volunteers treated with GSK1322322, a novel antibiotic targeting bacterial peptide deformylase Antimicrob Agents Chemother 59 1182-1192

Hann MM(2020)Metagenome-wide association analysis identifies microbial determinants of post-antibiotic ecological recovery in the gut Nature Ecology and Evolution 4 1256-1267

Hennessy A(2017)Recurrent urinary tract infections in women: risk factors, etiology, pathogenesis and prophylaxis Future Microbiol 12 239-246

Hibbs M(2016)In vitro activity of gepotidacin, a novel triazaacenaphthylene bacterial topoisomerase inhibitor, against a broad spectrum of bacterial pathogens Antimicrob Agents Chemother 60 1918-1923

Bax BD(2010)Type IIA topoisomerase inhibition by a new class of antibacterial agents Nature. 466 935-940

Chan PF(2016)Clostridium difficile colitis: pathogenesis and host defence Nat Rev Microbiol 14 609-620

Eggleston DS(2010)Association between the use of antibiotics in the first year of life and pediatric inflammatory bowel disease Am J Gastroenterol 105 2687-2692

Fosberry A(2019)Association between antibiotics in the first year of life and celiac disease Gastroenterology. 156 2217-2229

Gentry DR(2018)Extensive impact of non-antibiotic drugs on human gut bacteria Nature. 555 623-628

Gorrec F(2016)Alekseyenko a v., Gao Z, et al. effect of antibiotic pre-treatment and pathogen challenge on the intestinal microbiota in mice Gut Pathogens 8 1-10

Giordano I(2015)Microbiome changes in healthy volunteers treated with GSK1322322, a novel antibiotic targeting bacterial peptide deformylase Antimicrob Agents Chemother 59 1182-1192

Hann MM(2020)Metagenome-wide association analysis identifies microbial determinants of post-antibiotic ecological recovery in the gut Nature Ecology and Evolution 4 1256-1267

Hennessy A(2017)Recurrent urinary tract infections in women: risk factors, etiology, pathogenesis and prophylaxis Future Microbiol 12 239-246

Hibbs M(2016)In vitro activity of gepotidacin, a novel triazaacenaphthylene bacterial topoisomerase inhibitor, against a broad spectrum of bacterial pathogens Antimicrob Agents Chemother 60 1918-1923