Regulation of TRP channels by PIP2

被引：0
作者：
Tibor Rohacs
机构：
[1] University of Medicine and Dentistry of New Jersey-New Jersey Medical School,Department of Pharmacology and Physiology
来源：
Pflügers Archiv - European Journal of Physiology | 2007年 / 453卷
关键词：
TRP channels; PIP; PtdIns(4,5)P; Phosphoinositides; Ion channels; TRPM channels; TRPV channels; TRPC channels;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Transient receptor potential (TRP) channels are regulated by a wide variety of physical and chemical factors. Recently, several members of the TRP channel family were reported to be regulated by phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2, PIP2). This review will summarize the current knowledge on PIP2 regulation of TRP channels and discuss the possibility that PIP2 is a common regulator of mammalian TRP channels.
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页码：753 / 762
页数：9
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