The role of iron and reactive oxygen species in cell death

被引:0
|
作者
Scott J Dixon
Brent R Stockwell
机构
[1] Columbia University,Department of Biological Sciences
[2] Columbia University,Department of Chemistry
[3] Columbia University,Department of Systems Biology
[4] Howard Hughes Medical Institute,undefined
[5] Columbia University,undefined
[6] Present address: Department of Biology,undefined
[7] Stanford University,undefined
[8] Stanford,undefined
[9] California,undefined
[10] USA.,undefined
来源
Nature Chemical Biology | 2014年 / 10卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Iron is essential for biological systems but can also damage or kill cells, leading to a variety of disease states. A review of mechanisms leading to Fe- and ROS-dependent cell death highlights the vast array of open questions in this complex field.[graphic not available: see fulltext]
引用
收藏
页码:9 / 17
页数:8
相关论文
共 50 条
  • [1] The role of iron and reactive oxygen species in cell death
    Dixon, Scott J.
    Stockwell, Brent R.
    NATURE CHEMICAL BIOLOGY, 2014, 10 (01) : 9 - 17
  • [2] Role of reactive oxygen species in the mitochondrial regulation of cell death
    Orrenius, Sten
    FREE RADICAL RESEARCH, 2009, 43 : 27 - 27
  • [3] PROTECTIVE ROLE OF REACTIVE OXYGEN SPECIES IN PANCREATIC ACINAR CELL DEATH
    Booth, D.
    Petersen, O. H.
    Sutton, R.
    Criddle, D. N.
    PANCREAS, 2008, 37 (04) : 463 - 463
  • [4] Analysis of reactive oxygen species in cell death
    Stamenkovic, I
    METHODS IN CELL BIOLOGY, VOL 66: APOPTOSIS, 2001, 66 : 307 - 319
  • [5] Reactive oxygen species in plant cell death
    Van Breusegem, Frank
    Dat, James F.
    PLANT PHYSIOLOGY, 2006, 141 (02) : 384 - 390
  • [6] Neuronal Cell Death and Reactive Oxygen Species
    Alexander Boldyrev
    Renjie Song
    Vladimir A. Dyatlov
    David A. Lawrence
    David O. Carpenter
    Cellular and Molecular Neurobiology, 2000, 20 : 433 - 450
  • [7] Neuronal cell death and reactive oxygen species
    Boldyrev, A
    Song, RJ
    Dyatlov, VA
    Lawrence, DA
    Carpenter, DO
    CELLULAR AND MOLECULAR NEUROBIOLOGY, 2000, 20 (04) : 433 - 450
  • [8] The role of reactive oxygen species and autophagy in safingol-induced cell death
    L-U Ling
    K-B Tan
    H Lin
    G N C Chiu
    Cell Death & Disease, 2011, 2 : e129 - e129
  • [9] The role of reactive oxygen species and autophagy in safingol-induced cell death
    Ling, L-U
    Tan, K-B
    Lin, H.
    Chiu, G. N. C.
    CELL DEATH & DISEASE, 2011, 2 : e129 - e129
  • [10] The role of ethylene in regulating reactive oxygen species-mediated cell death
    Kangasjärvi, J
    Overmyer, K
    Tuominen, H
    Keinänen, M
    BIOLOGY AND BIOTECHNOLOGY OF THE PLANT HORMONE ETHYLENE III, 2003, 349 : 328 - 334