Comparative Single-Dose Bioavailability Study of Two Oral Formulations of Ibuprofen in Healthy Volunteers

被引：0
|
作者：
A. Portolés
E. Vargas
M. García
A. Terleira
M. Rovira
M. C. Caturla
A. Moreno
机构：
[1] Hospital Clínico San Carlos,Unidad de Estudios de Farmacología Clínica, Servicio de Farmacología Clínica
[2] MCC Analítica,Servicio de Farmacología Clínica
[3] Hospital Clinico San Carlos,undefined
来源：
Clinical Drug Investigation | 2001年 / 21卷
关键词：
Ibuprofen; Oral Suspension; Antipyretic Effect; Phenylpropionic Acid; Free Acid Form;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Objective: To compare the bioavailability of equivalent doses of two oral formulations of ibuprofen: ibuprofen lysinate 1025mg (powder for oral suspension) and ibuprofen free acid 600mg (effervescent granules).
引用
收藏
页码：383 / 389
页数：6
相关论文
共 50 条
  • [21] Comparative bioavailability of two capsule formulations of ofloxacin in healthy volunteers after a single dose administration
    Oliveira, CF
    Dias, HB
    Ribeiro, W
    Poli, A
    Peixoto, AP
    Moraes, MEA
    Moraes, MO
    Bezerra, FAF
    Moreno, H
    Muscará, MN
    de Nucci, G
    CLINICAL RESEARCH AND REGULATORY AFFAIRS, 1999, 16 (1-2) : 29 - 40
  • [22] Comparative bioavailability of two losartan formulations in healthy human volunteers after a single dose administration
    Oliveira, CH
    Silva, RM
    Santagada, V
    Caliendo, G
    Perissutti, E
    Galuppo, MP
    Rezende, VM
    Barrientos-Astigarraga, RE
    Mendes, GD
    De Nucci, G
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2006, 44 (03) : 142 - 148
  • [23] Pharmacokinetics and comparative bioavailability of two metformin formulations after single-dose administration in healthy subjects
    Atanasova, I
    Bozhinova, K
    Todorova, D
    Terziivanov, D
    CLINICAL DRUG INVESTIGATION, 2003, 23 (11) : 743 - 749
  • [24] Pharmacokinetics and Comparative Bioavailability of Two Metformin Formulations after Single-Dose Administration in Healthy Subjects
    Ivanka Atanasova
    Kristina Bozhinova
    Denitza Todorova
    Dimiter Terziivanov
    Clinical Drug Investigation, 2003, 23 : 743 - 749
  • [25] Single-dose oral pharmacokinetics of three formulations of thalidomide in healthy male volunteers
    Teo, SK
    Colburn, WA
    Thomas, SD
    JOURNAL OF CLINICAL PHARMACOLOGY, 1999, 39 (11): : 1162 - 1168
  • [26] Comparative bioavailability evaluation of two cyclosporine oral formulations in healthy Mexican volunteers
    González-Llaven, J
    Palma-Aguirre, JA
    García-Arreola, R
    Brizuela, V
    Nava-Rangel, J
    Morán-Lira, S
    Vela-Ojeda, J
    Castañeda-Hernández, G
    Flores-Murrieta, FJ
    ARCHIVES OF MEDICAL RESEARCH, 1999, 30 (04) : 315 - 319
  • [27] Comparative Bioavailability of Two Diosmin Formulations after Oral Administration to Healthy Volunteers
    Russo, Rosario
    Chandradhara, Divya
    De Tommasi, Nunziatina
    MOLECULES, 2018, 23 (09):
  • [28] Comparative Bioavailability Study of a New Orodispersible Formulation of Ibuprofen Versus Two Existing Oral Tablet Formulations in Healthy Male and Female Volunteers
    Sugar, Dalma
    Francombe, Danielle
    da Silva, Tiago
    Hanid, Sarah
    Hutchings, Simon
    CLINICAL THERAPEUTICS, 2019, 41 (08) : 1486 - 1498
  • [29] COMPARATIVE BIOAVAILABILITY STUDY OF IBUPROFEN LYSINATE AND IBUPROFEN BASE ORAL SUSPENSIONS ADMINISTERED IN HEALTHY VOLUNTEERS
    Ferrero-Cafiero, J. M.
    Puntes, M.
    Martinez, J.
    Ballester, M. R.
    Coimbra, J.
    Matheson, Y.
    Antonijoan, R. M.
    Tarre, M.
    Font, X.
    Gich, I.
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2014, 115 : 29 - 30
  • [30] Comparative bioavailability of two sertraline tablet formulations in healthy human volunteers after a single dose administration
    Moraes, MEA
    Lerner, FE
    Perozin, M
    Moraes, MO
    Bezerra, FAF
    Sucupira, M
    Corso, G
    De Nucci, G
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 1998, 36 (12) : 661 - 665
12345