Comparative Single-Dose Bioavailability Study of Two Oral Formulations of Ibuprofen in Healthy Volunteers

被引:0
|
作者
A. Portolés
E. Vargas
M. García
A. Terleira
M. Rovira
M. C. Caturla
A. Moreno
机构
[1] Hospital Clínico San Carlos,Unidad de Estudios de Farmacología Clínica, Servicio de Farmacología Clínica
[2] MCC Analítica,Servicio de Farmacología Clínica
[3] Hospital Clinico San Carlos,undefined
来源
关键词
Ibuprofen; Oral Suspension; Antipyretic Effect; Phenylpropionic Acid; Free Acid Form;
D O I
暂无
中图分类号
学科分类号
摘要
Objective: To compare the bioavailability of equivalent doses of two oral formulations of ibuprofen: ibuprofen lysinate 1025mg (powder for oral suspension) and ibuprofen free acid 600mg (effervescent granules).
引用
收藏
页码:383 / 389
页数:6
相关论文
共 50 条
  • [1] Comparative single-dose bioavailability study of two oral formulations of ibuprofen in healthy volunteers
    Portolés, A
    Vargas, E
    García, M
    Terleira, A
    Rovira, M
    Caturla, MC
    Moreno, A
    CLINICAL DRUG INVESTIGATION, 2001, 21 (05) : 383 - 389
  • [2] A comparative bioavailability study of two ibuprofen formulations after single-dose administration in healthy volunteers
    Wiria, Metta Sinta Sari
    Suyatna, Fransiscus D.
    MEDICAL JOURNAL OF INDONESIA, 2007, 16 (03) : 181 - 186
  • [3] Comparative bioavailability of two ramipril formulations after single-dose administration in healthy volunteers
    Mendes, GD
    Sanfelice, ATD
    Borges, NCD
    Cavedal, LE
    Sverdloff, C
    Galuppo, MP
    Módolo, JH
    De Nucci, G
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2006, 44 (02) : 93 - 98
  • [4] Comparative bioavailability of two cefadroxil formulations in healthy human volunteers after a single-dose administration
    Oliveira, CH
    Salmon, J
    Sucupira, M
    Ilha, J
    De Nucci, G
    BIOPHARMACEUTICS & DRUG DISPOSITION, 2000, 21 (06) : 243 - 247
  • [5] Comparative bioavailability of two sertraline tablet formulations after single-dose administration in healthy Thai volunteers
    Tassaneeyakul, W.
    Kanchanawat, S.
    Gaysonsiri, D.
    Vannaprasath, S.
    Paupairoj, R.
    Kittiwattanagul, K.
    Tippabhotla, S. K.
    Khuroo, A.
    Panigrahy, B. K.
    Reyar, S.
    Monif, T.
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2008, 46 (03) : 151 - 156
  • [6] COMPARATIVE BIOAVAILABILITY OF TWO SILDENAFIL TABLET FORMULATIONS AFTER SINGLE-DOSE ADMINISTRATION IN HEALTHY THAI MALE VOLUNTEERS
    Kanjanawart, Sirimas
    Vannaprasaht, Suda
    Tangsucharit, Panot
    Gaysornsiri, Dhanu
    Tiamkao, Siriporn
    Kongyingyoes, Bunkerd
    Tangrassameeprasert, Roongpet
    Tassaneeyakul, Wongwiwat
    Tassaneeyakul, Wichittra
    DRUG METABOLISM REVIEWS, 2007, 39 : 87 - 87
  • [7] Comparative bioavailability of two sildenafil tablet formulations after single-dose administration in healthy Thai male volunteers
    Kanjanawart, S.
    Gaysonsiri, D.
    Tangsucharit, P.
    Vannaprasaht, S.
    Phunikhom, K.
    Kaewkamson, T.
    Wattanachai, N.
    Tassaneeyakul, W.
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2011, 49 (08) : 525 - 530
  • [8] Comparative bioavailability study of two oral formulations of ibuprofen
    Corpetti, G
    Rosignoli, MT
    Dionisio, P
    ARZNEIMITTELFORSCHUNG-DRUG RESEARCH, 1998, 48 (04): : 392 - 395
  • [9] Comparative bioavailability of two oral formulations of bromazepam in healthy volunteers
    Lerner, FE
    Schere, D
    Batafarano, N
    Casas, F
    Glancszpigel, R
    ARZNEIMITTEL-FORSCHUNG-DRUG RESEARCH, 2001, 51 (12): : 955 - 958
  • [10] A single-dose, food-effect and relative bioavailability study of tablet and oral formulations of rivoglitazone in healthy volunteers
    Walker, J. R.
    Yoshioka, S.
    Izumi, T.
    Wang, A.
    Wickremasingha, P.
    Chou, H.
    Truitt, K. E.
    JOURNAL OF CLINICAL PHARMACOLOGY, 2008, 48 (09): : 1109 - 1109