The updated WHO classification of digestive system tumours—gastric adenocarcinoma and dysplasiaDie aktuelle WHO-Klassifikation der Tumoren des Verdauungstrakts – Dysplasie und Adenokarzinom des Magens

被引:0
|
作者
R. Kushima
机构
[1] Shiga University of Medical Science,Department of Pathology
来源
Der Pathologe | 2022年 / 43卷 / 1期
关键词
Histology; Carcinoma, signet ring cell; Cell differentiation; Neoplasms; Pathology, molecular; Histologie; Siegelringzellkarzinom; Zelldifferenzierung; Neoplasien; Molekularpathologie;
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摘要
The fifth edition of the World Health Organization (WHO) classification of digestive system tumours was published in 2019. The classification of invasive carcinoma is basically the same as in the fourth edition, but the description of each histological type has been updated, and some rare subtypes such as micropapillary carcinoma, gastric adenocarcinoma of the fundic gland type and undifferentiated carcinoma have been added and explained. Although this classification did not provide specific numerical criteria for the diagnosis of signet-ring cell carcinoma in poorly cohesive carcinoma, an additional study defined signet-ring cell carcinoma as having more than 90% signet-ring cells. The molecular classification of gastric cancer (Epstein–Barr virus-positive type, microsatellite instability type, genomically stable type, chromosomally unstable type) was additionally introduced. Many pages in the present classification have been devoted to precancerous lesions, and this article focuses on foveolar-type adenoma/dysplasia.
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页码:8 / 15
页数:7
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