Insulin-mediated capillary recruitment in skeletal muscle: Is this a mediator of insulin action on glucose metabolism?

被引：13
作者：
Stephen Rattigan
Eugene J. Barrett
Michael G. Clark
机构：
[1] Department of Biochemistry, Medical School, University of Tasmania, Hobart, Tas. 7001
来源：
Current Diabetes Reports | 2003年 / 3卷 / 3期
基金：
美国国家卫生研究院; 英国医学研究理事会;
关键词：
Glucose Uptake; Human Skeletal Muscle; AICAR; Muscle Blood Flow; Muscle Glucose Uptake;
D O I：
10.1007/s11892-003-0063-4
中图分类号：
学科分类号：
摘要：
The possibility that insulin stimulates microvascular access for itself and glucose in muscle in vivo is discussed. The application of new techniques suggests that capillary recruitment is a normal part of insulin's action and that this process becomes impaired in insulin resistance. Exercise, which also leads to capillary recruitment, may involve a different mechanism than that used by insulin. Copyright © 2003 by Current Science Inc.
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收藏
页码：195 / 200
页数：5
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