Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation

被引:0
作者
Michael R Wasserman
Jose L Alejo
Roger B Altman
Scott C Blanchard
机构
[1] Weill Cornell Medical College,Department of Physiology and Biophysics
[2] Tri-Institutional Training Program in Chemical Biology,undefined
[3] Weill Cornell Medical College,undefined
来源
Nature Structural & Molecular Biology | 2016年 / 23卷
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摘要
Monitoring ribosomal translocation from five structural perspectives with pre–steady state smFRET defines intramolecular conformational events within the EF-G–GDP–bound ribosome as rate-determining steps of directional substrate translocation.
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页码:333 / 341
页数:8
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