miR-29b and miR-198 overexpression in CD8+ T cells of renal cell carcinoma patients down-modulates JAK3 and MCL-1 leading to immune dysfunction

被引：0
作者：
Margherita Gigante
Paola Pontrelli
Wolfgang Herr
Maddalena Gigante
Morena D’Avenia
Gianluigi Zaza
Elisabetta Cavalcanti
Matteo Accetturo
Giuseppe Lucarelli
Giuseppe Carrieri
Michele Battaglia
Walter J. Storkus
Loreto Gesualdo
Elena Ranieri
机构：
[1] University of Bari,Department of Emergency and Organ Transplantation
[2] University Medical Center of Regensburg,Department of Medicine III, Hematology and Oncology
[3] University of Foggia,Department of Medical and Surgical Sciences, Faculty of Medicine
[4] University of Bari,Department of Internal Medicine and Oncology
[5] University of Verona,Renal Unit, Department of Medicine
[6] University of Pittsburgh,Department of Dermatology and Immunology
来源：
Journal of Translational Medicine | / 14卷
关键词：
Renal cell carcinoma; CD8; T cells; Apoptosis; miRNA; JAK3; MCL-1;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 202 条
[1]  
Carthew RW(2009)Origins and mechanisms of miRNAs and siRNAs Cell 136 642-655
[2]  
Sontheimer EJ(2004)MicroRNAs: genomics, biogenesis, mechanism, and function Cell 116 281-297
[3]  
Bartel DP(2007)microRNAs and cell cycle regulation Cell Cycle 6 2127-2132
[4]  
Carleton M(2013)microRNA regulation of T-cell differentiation and function Immunol Rev 253 65-81
[5]  
Cleary MA(2015)microRNAs function in CD8 J Leukoc Biol 97 487-497
[6]  
Linsley PS(2013)T cell biology Curr Opin Genet Dev 23 3-11
[7]  
Jeker LT(2010)miRNA profiling of cancer Mod Pathol 23 1577-1582
[8]  
Bluestone JA(2010)miRNA expression profiling of lung adenocarcinomas: correlation with mutational status Mod Pathol 23 1567-1576
[9]  
Liang Y(2010)Biologic profiling of lymph node negative breast cancers by means of microRNA expression Lancet Oncol. 12 136-146
[10]  
Pan HF(2010)Relation between microRNA expression and progression and prognosis of gastric cancer: a microRNA expression analysis Urology. 75 835-841
12345678910