Biomarkers of Scleroderma Lung Disease: Recent Progress

被引：0
作者：
Faye N. Hant
Richard M. Silver
机构：
[1] Medical University of South Carolina,Division of Rheumatology and Immunology
来源：
Current Rheumatology Reports | 2011年 / 13卷
关键词：
Systemic sclerosis; Scleroderma; Interstitial lung disease; Biomarkers; SP-D; KL-6; TWEAK; APRIL; BAFF; Exhaled nitric oxide; PMN elastase;
D O I：
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学科分类号：
摘要：
This article reviews the clinical background and significance of selected biomarkers that have been studied in relation to systemic sclerosis, or scleroderma, a devastating connective tissue disease whose morbidity and mortality are often related to pulmonary complications. Interstitial lung disease is the most common pulmonary manifestation in systemic sclerosis, and the search for a noninvasive biomarker to assess and monitor patients and their lung disease is a nascent and expending field of study. In this article, we examine the background and significance of a variety of selected biomarkers and assess their role in relation to systemic sclerosis–related interstitial lung disease.
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页码：44 / 50
页数：6
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