Hsp90 up-regulates PD-L1 to promote HPV-positive cervical cancer via HER2/PI3K/AKT pathway

[1] Ajiro M(2015)E6^ E7, a novel splice isoform protein of human papillomavirus 16, stabilizes viral E6 and E7 oncoproteins via HSP90 and GRP78 MBio 36 893-899

[2] Zheng Z-M(2012)The apoptotic effect and associated signalling of HSP90 inhibitor 17-DMAG in hepatocellular carcinoma cells Cell Biol Int 8 e191-e203

[3] Am L(2020)Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis Lancet Glob Health 20 3446-3457

[4] Arbyn M(2014)Effects of MAPK and PI3K pathways on PD-L1 expression in melanoma Clin Cancer Res 164 177-187

[5] Atefi M(2019)Targeting hsp90 family members: a strategy to improve cancer cell death Biochem Pharmacol 4 1-6

[6] Calderon PB(2004)HER2 expression in cervical cancer as a potential therapeutic target BMC Cancer 89 101-105

[7] Beck R(2003)Comparison of HPV type distribution in high-grade cervical lesions and cervical cancer: a meta-analysis Br J Cancer 8 340-8

[8] Glorieux C(2019)Hsp90 inhibitors enhance the antitumoral effect of osimertinib in parental and osimertinib-resistant non-small cell lung cancer cell lines Transl Lung Cancer Res 9 1-953

[9] Chavez-Blanco A(2019)Synergistic activity of Hsp90 inhibitors and anticancer agents in pancreatic cancer cell cultures Sci Rep 29 942-890

[10] Clifford G(2020)SNX-2112, an Hsp90 inhibitor, suppresses cervical cancer cells proliferation, migration, and invasion by inhibiting the Akt/mTOR signaling pathway Med Chem Res 132 882-943

[1] Ajiro M(2015)E6^ E7, a novel splice isoform protein of human papillomavirus 16, stabilizes viral E6 and E7 oncoproteins via HSP90 and GRP78 MBio 36 893-899

[2] Zheng Z-M(2012)The apoptotic effect and associated signalling of HSP90 inhibitor 17-DMAG in hepatocellular carcinoma cells Cell Biol Int 8 e191-e203

[3] Am L(2020)Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis Lancet Glob Health 20 3446-3457

[4] Arbyn M(2014)Effects of MAPK and PI3K pathways on PD-L1 expression in melanoma Clin Cancer Res 164 177-187

[5] Atefi M(2019)Targeting hsp90 family members: a strategy to improve cancer cell death Biochem Pharmacol 4 1-6

[6] Calderon PB(2004)HER2 expression in cervical cancer as a potential therapeutic target BMC Cancer 89 101-105

[7] Beck R(2003)Comparison of HPV type distribution in high-grade cervical lesions and cervical cancer: a meta-analysis Br J Cancer 8 340-8

[8] Glorieux C(2019)Hsp90 inhibitors enhance the antitumoral effect of osimertinib in parental and osimertinib-resistant non-small cell lung cancer cell lines Transl Lung Cancer Res 9 1-953

[9] Chavez-Blanco A(2019)Synergistic activity of Hsp90 inhibitors and anticancer agents in pancreatic cancer cell cultures Sci Rep 29 942-890

[10] Clifford G(2020)SNX-2112, an Hsp90 inhibitor, suppresses cervical cancer cells proliferation, migration, and invasion by inhibiting the Akt/mTOR signaling pathway Med Chem Res 132 882-943