Enantiomeric separation of three chiral drugs by nonaqueous capillary electrophoresis with triethylamine as additive

被引:1
|
作者
Xueqin Ren
Aijin Huang
Tiansong Wang
Yiliang Sun
Zengpei Sun
机构
[1] Peking University,Department of Chemistry
[2] National Institute for the Control of Pharmaceutical and Biological Products,undefined
来源
Chromatographia | 1999年 / 50卷
关键词
Capillary electrophoresis; Enantioseparation; Non-aqueous media; Triethylamine;
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学科分类号
摘要
The enantiomeric separation of chiral drugs by capillary electrophoresis (CE) in nonaqueous system has been investigated. Successful separation of bepridil, ondansetron and pinacidil in formamide using β-cyclodextrin as chiral selector were achieved. The addition of triethylamine into the background electrolyte enhanced the enantiomeric discrimination.
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页码:625 / 628
页数:3
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