Synthesis of 9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2Н,5Н)-diones

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作者
O. E. Nasakin
M. I. Kazantseva
V. L. Gein
机构
[1] Chuvash State University,
[2] Perm State Pharmaceutical Academy,undefined
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9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2; ,5; )-dione; Hantzsch synthesis; antimicrobial activity;
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摘要
The reaction in a mixture of 1,3-cyclohexanedione (dimedone), arylaldehyde, and ammonium acetate at 160°C during 10–15 min in the absence of solvent leads to the formation of 9-aryl-3,4,6,7,9,10-hexahydroacridine-1,8(2H,5H)-diones. The structure of the products has been confirmed by IR and 1H NMR spectroscopy data. Antimicrobial activity of the obtained compounds has been studied.
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页码:154 / 155
页数:1
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