Stress, bacterial vaginosis, and the role of immune processes

被引：37
作者：
Culhane J.F. [1 ]
Rauh V.A. [1 ]
Goldenberg R.L. [1 ]
机构：
[1] Drexel University College of Medicine, Department of Obstetrics/Gynecology, Philadelphia, PA 19102
来源：
Current Infectious Disease Reports | 2006年 / 8卷 / 6期
关键词：
Preterm Birth; Black Woman; Obstet Gynecol; Bacterial Vaginosis; Psychosocial Stress;
D O I：
10.1007/s11908-006-0020-x
中图分类号：
学科分类号：
摘要：
Bacterial vaginosis (BV), the most common lower genital tract infection in women of reproductive age, is associated with adverse gynecologic and reproductive health outcomes. Women at highest risk for BV are young, unmarried, low income, undereducated, and African American. Behaviors such as vaginal douching, numerous sexual partners, frequent sexual intercourse, receptive oral sex, and substance use may contribute to risk, but they account for only a modest proportion of the observed race/ ethnicity variance in BV. These subpopulations are also exposed to more social disadvantages or "stressors" such as poverty, poor housing, crime-infested neighborhoods, and discrimination than other groups. Growing physiologic evidence links psychosocial stress to the development of disease. Evidence supports a statistically significant, independent effect of stress on the risk and observed racial/ethnic disparity in the rate of BV. This paper reviews such evidence. Copyright © 2006 by Current Science Inc.
引用
收藏
页码：459 / 464
页数：5
相关论文
共 63 条
[21]  
Schmid G.P., The epidemiology of bacterial vaginosis, Int J Gynaecol Obstet, 67, SUPPL. 1, pp. 17-20, (1999)
[22]  
Biondi M., Zannino L.G., Psychosocial stress, neuroimmunomodulation, and susceptibility to infectious diseases in animal and man: A review, Psychother Psychosom, 66, pp. 3-26, (1997)
[23]  
Cohen S., Tyrrell D.A., Smith A.P., Psychological stress and susceptibility to the common cold, N Engl J Med, 325, pp. 606-612, (1991)
[24]  
Glaser R., Rabin B., Chesney M., Et al., Stress-induced immunomodulation: Implications for infectious diseases?, JAMA, 281, pp. 2268-2270, (1999)
[25]  
Herbert T.B., Cohen S., Stress and immunity in humans, Psychosom Med, 55, pp. 364-379, (1993)
[26]  
Boyce W.T., Chesney M., Alkon A., Et al., Psychobiologic reactivity to stress and childhood respiratory illnesses: Results of two prospective studies, Psychosom Med, 57, pp. 411-422, (1995)
[27]  
Glaser R., Kiecolt-Glaser J., Malarkey W., Et al., Stress-induced modulation of the immune responses to recombinant Hepatitis B vaccine, Psychosom Med, 54, pp. 22-29, (1992)
[28]  
Kiecolt-Glaser J., Marucha P., Malarkey W., Et al., Slowing of wound healing by psychological stress, Lancet, 346, pp. 1194-1196, (1995)
[29]  
Evans D.L., Leserman J., Perkins D.O., Et al., Severe life stress as a predictor of early disease progression in HIV infection, Am J Psychiatry, 154, pp. 630-634, (1997)
[30]  
Leserman J., Jackson E.D., Petitto J.M., Et al., Progression to AIDS: The effects of stress, depressive symptoms, and social support, Psychosom Med, 61, pp. 397-406, (1999)
1234567