Chronic pancreatitis

被引：10

作者：

Mayerle J. ^{[1
]}

Stier A. ^{[2
]}

Lerch M.M. ^{[1
]}

Heidecke C.-D. ^{[2
,3
]}

机构：

[1] Abt. Gastroenterol., Endokrinol. E., Universitätsklinikum Greifswald, Ernst-Moritz-Arndt-Universität, Greifswald

[2] Abt. Allg. Chir., Viszeral-, T., Universitätsklinikum Greifswald, Ernst-Moritz-Arndt-Universität, Greifswald

[3] Abt. Allg. Chir., Viszeral-, T., Universitätsklinikum Greifswald, Ernst-Moritz-Arndt-Universität, 17487 Greifswald

来源：

Der Chirurg | 2004年 / 75卷 / 7期

关键词：

Chronic pancreatitis; Duodenum-preserving pancreatic head resection; Hereditary pancreatitis; Idiopathic pancreatitis; pp-Whipple;

D O I：

10.1007/s00104-004-0892-y

中图分类号：

学科分类号：

摘要：

Chronic pancreatitis is characterized by periodic episodes of inflammation and loss of exocrine and endocrine function of the pancreas. Hereditary pancreatitis is an autosomal dominant disorder with an 80% penetrance, is associated with recurrent episodes of pancreatitis starting in early childhood and correlated to an increased risk of pancreatic cancer. The pathogenesis of chronic and hereditary pancreatitis is not yet fully understood. Patients suffering from chronic pancreatitis present with belt-like abdominal pain, weight loss, and often diabetes mellitus. The diagnosis is made by a combination of imaging procedures such as ultrasound and endoscopic retrograde cholangiopancreatography and exocrine and endocrine function tests. Therapy is restricted to symptom control. Approximately 30-60% of all patients develop disease-associated complications such as persistent pain, strictures of the common bile duct, or pancreatic duct stones which require either interventional or surgical treatment.

引用

页码：731 / 748

页数：17

共 24 条

[1]

Ammann R.W., Akovbiantz A., Largiader F., Schueler G., Course and outcome of chronic pancreatitis. Longitudinal study of a mixed medicalsurgical series of 245 patients, Gastroenterology, 86, pp. 820-828, (1984)

[2]

Beger H.G., Schlosser W., Friess H.M., Buchler M.W., Duodenum-preserving head resection in chronic pancreatitis changes the natural course of the disease: A single-center 26-year experience, Ann Surg, 230, pp. 512-519, (1999)

[3]

Buchler M.W., Friess H., Muller M.W., Et al., Randomized trial of duodenum-preserving pancreatic head resection versus pylorus-preserving Whipple in chronic pancreatitis, Am J Surg, 169, pp. 65-69, (1995)

[4]

Chowdhury R.S., Forsmark C.E., Review article: Pancreatic function testing, Aliment Pharmacol Ther, 17, pp. 733-750, (2003)

[5]

Etemad B., Whitcomb D.C., Chronic pancreatitis: Diagnosis, classification, and new genetic developments, Gastroenterology, 120, pp. 682-707, (2001)

[6]

Friess H., Berberat P.O., Wirtz M., Buchler M.W., Surgical treatment and long-term follow up in chronic pancreatitis, Eur J Gastroenterol Hepatol, 14, pp. 971-977, (2002)

[7]

Glasbrenner B., Kahl S., Malfertheiner P., Modern diagnostic of chronic pancreatitis, Europ J Gastro Hepat, 14, pp. 935-941, (2002)

[8]

Gloor B., Friess H., Uhl W., Buchler M.W., A modified technique of the Beger and Frey procedure in patients with chronic pancreatitis, Dig Surg, 18, pp. 21-25, (2000)

[9]

Ho H.S., Frey C.F., The Frey procedure: Local resection of pancreatic head combined with lateral pancreaticojejunostomy, Arch Surg, 136, pp. 1353-1358, (2001)

[10]

Howard T.J., Swofford J.B., Wagner D., Et al., Quality of life after bilateral thorascopic splanchnicectomy: Long term evaluation in patients with chronic pancreatitis, J Gastrointest Surg, 6, pp. 845-854, (2002)

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