Prognosis and Biology in Esthesioneuroblastoma: the Emerging Role of Hyams Grading System

被引：0
作者：
Rami E. Saade
Ehab Y. Hanna
Diana Bell
机构：
[1] The University of Texas MD Anderson Cancer Center,Department of Head and Neck Surgery
[2] The University of Texas MD Anderson Cancer Center,Department of Neurosurgery, Division of Surgery
[3] The University of Texas MD Anderson Cancer Center,Departement of Pathology
来源：
Current Oncology Reports | 2015年 / 17卷
关键词：
Esthesioneuroblastoma; Olfactory Neuroblastoma; Hyams; Kadish; Morita; Stage; Grade; Prognosis; Outcome;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Esthesioneuroblastoma is a sinonasal tumor with distinct clinicopathologic features, multiple facets, and a spectrum of behavior. Characterization of this disease is challenging, and clinically, several staging systems have been used with no consensus on a single scheme. Recently, the Hyams histological grading system has emerged as a promising prognostication tool that offers an added value to stage. This review addresses prognosis and biology in esthesioneuroblastoma. More specifically, we sought to present a critical appraisal on the value of each of these stratification systems, stage vs. grade, in identifying risk groups and guiding management.
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