Primary parotid gland lymphoma: A case report

被引:4
作者
Konofaos P. [1 ]
Spartalis E. [1 ]
Katsaronis P. [1 ]
Kouraklis G. [1 ]
机构
[1] 2nd Department of Propedeutic Surgery, 'Laiko' General Hospital 17, Ag Thomas Street
关键词
Salivary Gland; Parotid Gland; Mucosa Associate Lymphoid Tissue; Marginal Zone Lymphoma; Mucosa Associate Lymphoid Tissue Lymphoma;
D O I
10.1186/1752-1947-5-380
中图分类号
学科分类号
摘要
Introduction. Mucosa associated lymphoid tissue lymphomas are the most common lymphomas of the salivary glands. The benign lymphoepithelial lesion is also a lymphoproliferative disease that develops in the parotid gland. In the present case report, we describe one case of benign lymphoepithelial lesion with a subsequent low transformation to grade mucosa associated lymphoid tissue lymphoma appearing as a cystic mass in the parotid gland. Case presentation. A 78-year-old Caucasian female smoker was referred to our clinic with a non-tender left facial swelling that had been present for approximately three years. The patient underwent resection of the left parotid gland with preservation of the left facial nerve through a preauricular incision. The pathology report was consistent with a low-grade marginal-zone B-cell non-Hodgkin lymphoma (mucosa associated lymphoid tissue lymphoma) following benign lymphoepithelial lesion of the gland. Conclusions: Salivary gland mucosa associated lymphoid tissue lymphoma should be considered in the differential diagnosis of cystic or bilateral salivary gland lesions. Parotidectomy is recommended in order to treat the tumor and to ensure histological diagnosis for further follow-up planning. Radiotherapy and chemotherapy should be considered in association with surgery in disseminated forms or after removal. © 2011 Petros et al; licensee BioMed Central Ltd.
引用
收藏
相关论文
共 42 条
  • [1] Wolvius E.B., Van Der Valk P., Van Der Wal J.E., Van Diest P.J., Huijgens P.C., Van Der Waal I., Snow G.B., Primary non-Hodgkin's lymphoma of the salivary glands. An analysis of 22 cases, Journal of Oral Pathology and Medicine, 25, 4, pp. 177-181, (1996)
  • [2] Isaacson P.G., Norton A.J., Extranodal Lymphomas, (1994)
  • [3] Azzopardi J.G., Evans D.J., Malignant lymphoma of parotid associated with Mikulicz disease (benign lymphoepithelial lesion), J Clin Path, 24, pp. 744-752, (1971)
  • [4] Batsakis J.G., Bernacki E.G., Rice D.H., Stebler M.F., Malignancy and the benign lymphoepithelial lesion, Laryngoscope, 85, pp. 389-399, (1975)
  • [5] Isaacson P., Wright D.H., Malignant lymphoma of mucosa-associated lymphoid tissue. A distinctive type of B-cell lymphoma, Cancer, 52, 8, pp. 1410-1416, (1983)
  • [6] Anacak Y., Miller R.C., Constantinou N., Mamusa A.M., Epelbaum R., Li Y., Calduch A.L., Kowalczyk A., Weber D.C., Kadish S.P., Bese N., Poortmans P., Kamer S., Ozsahin M., Primary Mucosa-Associated Lymphoid Tissue Lymphoma of the Salivary Glands: A Multicenter Rare Cancer Network Study, Int J Radiat Oncol Biol Phys, (2010)
  • [7] Balm A.J.M., Delaere P., Hilgers F.J.M., Somers R., Van Heerde P., Primary lymphoma of mucosa associated lymphoid tissue (MALT) in the parotid gland, Clinical Otolaryngology and Allied Sciences, 18, 6, pp. 528-532, (1993)
  • [8] Gleeson M.J., Bennett M.H., Cawson R.A., Lymphomas of the salivary glands, Cancer, 58, pp. 699-704, (1986)
  • [9] Hyman G.A., Wolff M., Malignant lymphomas of the salivary glands. Review of the literature and report of 33 new cases, including four cases associated with the lymphoepithelial lesion, Am J Clin Pathol, 65, pp. 421-438, (1976)
  • [10] Mehle M.E., Kraus D.H., Wood B.G., Lymphoma of the parotid glands, Laryngoscope, 103, pp. 17-21, (1993)