TREM-1 triggers necroptosis of macrophages through mTOR-dependent mitochondrial fission during acute lung injury

被引:0
作者
Wen-Jing Zhong
Jun Zhang
Jia-Xi Duan
Chen-Yu Zhang
Sheng-Chao Ma
Yu-Sheng Li
Nan-Shi-Yu Yang
Hui-Hui Yang
Jian-Bing Xiong
Cha-Xiang Guan
Zhi-Xing Jiang
Zhi-Jian You
Yong Zhou
机构
[1] Central South University,Department of Physiology, School of Basic Medical Science
[2] Hunan University of Medicine,Department of Physiology
[3] Ningxia Medical University,NHC Key Laboratory of Metabolic Cardiovascular Diseases Research
[4] Ningxia Medical University,The School of Basic Medical Sciences
[5] Xiangya Hospital,Department of Orthopedics
[6] Central South University,Department of Anesthesiology
[7] Liuzhou People’s Hospital,Liuzhou Key Laboratory of Anesthesia and Brain Health
[8] Liuzhou People’s Hospital,undefined
来源
Journal of Translational Medicine | / 21卷
关键词
Acute lung injury; TREM-1; Macrophages; Necroptosis; Mitochondrial fission; mTOR;
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[51]  
Hegedus C(2012)Mitochondrial fission, fusion, and stress Science 168 undefined-undefined
[52]  
Kovacs K(2020)Drp1-dependent mitochondrial fission contributes to Cr(VI)-induced mitophagy and hepatotoxicity Ecotoxicol Environ Saf 130 undefined-undefined
[53]  
Kufer TA(2012)Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy Nat Chem Biol 1865 undefined-undefined
[54]  
Virag L(2008)Fission and selective fusion govern mitochondrial segregation and elimination by autophagy EMBO J 20 undefined-undefined
[55]  
Jiang HL(2022)The role of mitochondrial fission in cardiovascular health and disease Nat Rev Cardiol 11 undefined-undefined
[56]  
Yang HH(2017)mTOR signaling in growth, metabolism, and disease Cell 148 undefined-undefined
[57]  
Liu YB(2020)Gut epithelial TSC1/mTOR controls RIPK3-dependent necroptosis in intestinal inflammation and cancer J Clin Invest 66 undefined-undefined
[58]  
Zhang CY(2019)mTORC1 inhibition attenuates necroptosis through RIP1 inhibition-mediated TFEB activation Biochim Biophys Acta Mol Basis Dis 12 undefined-undefined
[59]  
Zhong WJ(2019)Mitochondrial fragmentation limits NK cell-based tumor immunosurveillance Nat Immunol 18 undefined-undefined
[60]  
Guan XX(2020)Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics Nat Commun 18 undefined-undefined