Levels of serum-soluble receptor for interleukin-2 in patients with colorectal cancer

被引：0
|
作者：
Hiroaki Saito
Shunichi Tsujitani
Kuniyuki Katano
Masahide Ikeguchi
Michio Maeta
Nobuaki Kaibara
机构：
[1] Tottori University School of Medicine,First Department of Surgery
来源：
Surgery Today | 1998年 / 28卷
关键词：
interleukin-2 receptor; colorectal cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The preoperative levels of serum-soluble receptor for interleukin-2 (IL-2R) were determined by an enzyme-linked immunosorbent assay in 38 patients undergoing surgery for colorectal cancer and 98 healthy controls. The levels of serum-soluble IL-2R in the patients with colorectal cancer were significantly higher than those in the normal controls (P<0.05). Markedly elevated levels of serum-soluble IL-2R were recognized in patients with stage IV cancer, those with Dukes' stage D cancer, and those with liver metastasis. Moreover, the prognosis of patients with low levels of IL-2R (<531 U/ml) was significantly better than that of those with high levels (P<0.05). These findings demonstrate that an elevated concentration of soluble IL-2R might be a useful indicator of liver metastasis and poor prognosis in patients with colorectal carcinoma.
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页码：1115 / 1117
页数：2
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