Opioid-induced respiratory depression increases hospital costs and length of stay in patients recovering on the general care floor

[1] Andersen LW(2016)Acute respiratory compromise on inpatient wards in the United States: incidence, outcomes, and factors associated with in-hospital mortality Resuscitation 105 123-129

[2] Berg KM(2009)Epidemiology of anesthesia-related mortality in the United States, 1999-2005 Anesthesiology 110 759-765

[3] Chase M(2012)Mortality after surgery in Europe: a 7 day cohort study Lancet 380 1059-1065

[4] Cocchi MN(2020)Prediction of opioid-induced respiratory depression on inpatient wards using continuous Capnography and Oximetry: an international prospective, Observational Trial Anesth Analg 131 1012-1024

[5] Massaro J(2015)Postoperative hypoxemia is common and persistent: a prospective blinded observational study Anesth Analg 121 709-715

[6] Donnino MW(2015)Predictors of delayed postoperative respiratory depression assessed from naloxone administration Anesth Analg 121 422-429

[7] Li G(2016)Predictors and outcomes following naloxone administration during phase I anesthesia recovery J Anesth 30 116-122

[8] Warner M(2018)Risk factors for opioid-induced respiratory depression in surgical patients: a systematic review and meta-analyses BMJ Open 8 e024086-18S

[9] Lang BH(2012)Clinical and economic burden of opioid use for postsurgical pain: focus on ventilatory impairment and ileus Pharmacotherapy 32 12S-223

[10] Huang L(2004)Respiratory and haemodynamic effects of acute postoperative pain management: evidence from published data Br J Anaesth 93 212-293

[1] Andersen LW(2016)Acute respiratory compromise on inpatient wards in the United States: incidence, outcomes, and factors associated with in-hospital mortality Resuscitation 105 123-129

[2] Berg KM(2009)Epidemiology of anesthesia-related mortality in the United States, 1999-2005 Anesthesiology 110 759-765

[3] Chase M(2012)Mortality after surgery in Europe: a 7 day cohort study Lancet 380 1059-1065

[4] Cocchi MN(2020)Prediction of opioid-induced respiratory depression on inpatient wards using continuous Capnography and Oximetry: an international prospective, Observational Trial Anesth Analg 131 1012-1024

[5] Massaro J(2015)Postoperative hypoxemia is common and persistent: a prospective blinded observational study Anesth Analg 121 709-715

[6] Donnino MW(2015)Predictors of delayed postoperative respiratory depression assessed from naloxone administration Anesth Analg 121 422-429

[7] Li G(2016)Predictors and outcomes following naloxone administration during phase I anesthesia recovery J Anesth 30 116-122

[8] Warner M(2018)Risk factors for opioid-induced respiratory depression in surgical patients: a systematic review and meta-analyses BMJ Open 8 e024086-18S

[9] Lang BH(2012)Clinical and economic burden of opioid use for postsurgical pain: focus on ventilatory impairment and ileus Pharmacotherapy 32 12S-223

[10] Huang L(2004)Respiratory and haemodynamic effects of acute postoperative pain management: evidence from published data Br J Anaesth 93 212-293