Chiral Separation of 4-Iminoflavan Derivatives on Several Polysaccharide-Based Chiral Stationary Phases by HPLC

被引：0
作者：
Ismahan Rahou
Nasser Belboukhari
Khaled Sekkoum
Abdelkarim Cheriti
Hassan Y. Aboul-Enein
机构：
[1] University of Bechar,Bioactive Molecules and Chiral Separation Laboratory, Faculty of Science and Technology
[2] University of Bechar,Phytochemistry and Organic Synthesis Laboratory, Faculty of Science and Technology
[3] National Research Center,Pharmaceutical and Medicinal Chemistry Department, Pharmaceutical and Drug Industries Research Division
来源：
Chromatographia | 2014年 / 77卷
关键词：
Column liquid chromatography; Polysaccharide-based chiral stationary phases; Chiral separation; -Aryl 4-iminoflavans;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The HPLC enantiomeric separation of seven 4-iminoflavans was successfully accomplished in the normal phase mode using six polysaccharide-based chiral stationary phases namely, Chiralcel®OD-H, Chiralcel®OD, Chiralcel®OJ, Chiralpak®AD, Chiralpak®IA and Chiralpak®IB under normal and polar organic phase modes. The resolution depended on nature and concentration of alcoholic modifier. The results demonstrate clearly that the chromatographic system based on the coated and immobilized type Chiralpak®IB and Chiralcel®OD-H CSPs provide a powerful analytical tool for enantiomeric separation of all the 4-iminoflavans used in this study.
引用
收藏
页码：1195 / 1201
页数：6
相关论文
共 50 条
[11]   Enantiomeric separation of precursors of rho-kinase inhibitors by HPLC on polysaccharide-based chiral stationary phases [J].
C. Vaccher ;
V. Wallez ;
P. Carato ;
M. P. Vaccher ;
J. P. Bonte .
Chromatographia, 2000, 52 :513-516
[12]   Enantiomeric separation of precursors of Rho-kinase inhibitors by HPLC on polysaccharide-based chiral stationary phases [J].
Vaccher, C ;
Wallez, V ;
Carato, P ;
Vaccher, MP ;
Bonte, JP .
CHROMATOGRAPHIA, 2000, 52 (7-8) :513-516
[13]   Chiral separation of aliphatic primary amino alcohols as o-phthaldialdehyde/mercaptoethanol derivatives on polysaccharide-based chiral stationary phases [J].
Dousa, Michal .
CHIRALITY, 2019, 31 (03) :202-210
[14]   Chiral separations in reversed-phase liquid chromatography: Evaluation of several polysaccharide-based chiral stationary phases for a separation strategy update [J].
Younes, Ahmed A. ;
Mangelings, Debby ;
Vander Heyden, Yvan .
JOURNAL OF CHROMATOGRAPHY A, 2012, 1269 :154-167
[15]   Comparative enantioseparation of planar chiral ferrocenes on polysaccharide-based chiral stationary phases [J].
Dessi, Alessandro ;
Sechi, Barbara ;
Dallocchio, Roberto ;
Chankvetadze, Bezhan ;
Perez-Baeza, Mireia ;
Cossu, Sergio ;
Mamane, Victor ;
Pale, Patrick ;
Peluso, Paola .
CHIRALITY, 2022, 34 (04) :609-619
[16]   Separation of 4-substituted 5-methylpiracetam stereoisomers on polysaccharide-based chiral stationary phases [J].
Kazoka, H. ;
Turovska, B. ;
Upmanis, T. .
JOURNAL OF CHROMATOGRAPHY OPEN, 2024, 5
[17]   HPLC Separation of Enantiomers of Some Chiral Carboxylic Acid Derivatives Using Polysaccharide-Based Chiral Columns and Polar Organic Mobile Phases [J].
Iza Matarashvili ;
Lali Chankvetadze ;
Tamar Tsintsadze ;
Tivadar Farkas ;
Bezhan Chankvetadze .
Chromatographia, 2015, 78 :473-479
[18]   HPLC Separation of Enantiomers of Some Chiral Carboxylic Acid Derivatives Using Polysaccharide-Based Chiral Columns and Polar Organic Mobile Phases [J].
Matarashvili, Iza ;
Chankvetadze, Lali ;
Tsintsadze, Tamar ;
Farkas, Tivadar ;
Chankvetadze, Bezhan .
CHROMATOGRAPHIA, 2015, 78 (7-8) :473-479
[19]   The effect of temperature on the separation of enantiomers with coated and covalently immobilized polysaccharide-based chiral stationary phases [J].
Matarashvili, Iza ;
Kobidze, Giorgi ;
Chelidze, Aluda ;
Dolidze, Gizo ;
Beridze, Nino ;
Jibuti, Giorgi ;
Farkas, Tivadar ;
Chankvetadze, Bezhan .
JOURNAL OF CHROMATOGRAPHY A, 2019, 1599 :172-179
[20]   Recent developments on polysaccharide-based chiral stationary phases for liquid-phase separation of enantiomers [J].
Chankvetadze, Bezhan .
JOURNAL OF CHROMATOGRAPHY A, 2012, 1269 :26-51
12345