Idiopathic thrombocytopenic purpura following allogeneic bone marrow transplantation – treatment with anti-D immunoglobulin

被引:0
作者
SJ Lee
W Hallowell Churchill
A Konugres
DG Gilliland
JH Antin
机构
[1] Brigham and Women’s Hospital,Department of Medicine, Division of Hematology/Oncology
[2] Harvard Medical School,Department of Medicine
[3] Brigham and Women’s Hospital,undefined
[4] Blood Bank,undefined
[5] Harvard Medical School,undefined
来源
Bone Marrow Transplantation | 1997年 / 19卷
关键词
idiopathic thrombocytopenic purpura; bone marrow transplantation; anti-D immunoglobulin; chronic graft-versus-host disease;
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摘要
A 38-year-old man developed idiopathic thrombocytopenic purpura (ITP) 8 months following allogeneic BMT while being treated for cGVHD with corticosteroids and tacrolimus (FK506). He received two courses of high-dose intravenous immunoglobulin (IvIG) which resulted in transient improvement. A single dose of intravenous anti-D immunoglobulin induced a durable response. Anti-D immunoglobulin is better tolerated, less complicated to administer, and less expensive than a course of IvIG.
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页码:173 / 174
页数:1
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