Interleukin-1β, tumor necrosis factor-α, and oxidative stress biomarkers in cows with acute Brucella abortus infection

被引：3

作者：

Ali A.-F. ^{[1
]}

Abdelwahab M.G. ^{[2
]}

机构：

[1] Department of Clinical Pathology, Faculty of Veterinary Medicine, Benha University, Banha

[2] Department of Animal Medicine (Infectious Diseases), Faculty of Veterinary Medicine, Benha University, Banha

来源：

Comparative Clinical Pathology | 2021年 / 30卷 / 2期

关键词：

Brucella abortus; Cows; Cytokines; Oxidative stress; Serology;

D O I：

10.1007/s00580-021-03213-4

中图分类号：

学科分类号：

摘要：

The aim of this study was to investigate the possible alterations in some cytokines and oxidative stress biomarkers in cows with acute Brucella abortus (B. abortus) infection. The study has been carried out on twenty-two cows’ sera. All serum samples were examined for brucellosis by indirect enzyme-linked immunosorbant assay (i-ELISA). Cows that were seronegative for B. abortus infection were used as a control group; meanwhile, cows that were diagnosed positive for B. abortus infection were used as an infected group. Cytokine profile and oxidative state markers showed significant increases in interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), malondialdehyde (MDA), and nitric oxide (NO) levels in B. abortus-infected cows in comparison with the control group. On the other hand, significant decreases in interleukin-10 (IL-10) and total antioxidant capacity (TAC) levels were reported in B. abortus-infected cows when compared with controls. © 2021, The Author(s), under exclusive licence to Springer-Verlag London Ltd. part of Springer Nature.

引用

页码：311 / 315

页数：4

共 50 条

[21] Crevicular fluid interleukin-1β, tumor necrosis factor-α, and interleukin-6 levels in renal transplant patients receiving cyclosporine A [J].

Atilla, G ;

Kütükçüler, N .

JOURNAL OF PERIODONTOLOGY, 1998, 69 (07) :784-790

[22] Immunoexpression of tumour necrosis factor-α interleukin-1α and interleukin-10 on odontogenic cysts and tumours [J].

Sa, M. C. ;

de Matos, F. R. ;

Conceicao, T. S. ;

Leitao, A. C. G. H. ;

Freitas, R. A. .

INTERNATIONAL ENDODONTIC JOURNAL, 2017, 50 (05) :437-445

[23] IMMUNOMODULATING FUNCTIONS OF TUMOR-NECROSIS-FACTOR AND INTERLEUKIN-1 INHIBITORS [J].

DAYER, JM .

JOURNAL OF RHEUMATOLOGY, 1992, 19 :59-60

[24] The contribution of interleukin-1 and tumor necrosis factor to periodontal tissue destruction [J].

Graves, DT ;

Cochran, D .

JOURNAL OF PERIODONTOLOGY, 2003, 74 (03) :391-401

[25] Tumor necrosis factor-α and interleukin-1β mediate endothelial permeability induced by lipopolysaccharide-stimulated whole blood [J].

Nooteboom, A ;

van der Linden, CJ ;

Hendriks, T .

CRITICAL CARE MEDICINE, 2002, 30 (09) :2063-2068

[26] Isoflurane attenuates pulmonary interleukin-1β and systemic tumor necrosis factor-α following mechanical ventilation in healthy mice [J].

Vaneker, M. ;

Santosa, J. P. ;

Heunks, L. M. ;

Halbertsma, F. J. ;

Snijdelaar, D. G. ;

van Egmond, J. ;

van den Brink, I. A. ;

van de Pol, F. M. ;

van der Hoeven, J. G. ;

Scheffer, G. J. .

ACTA ANAESTHESIOLOGICA SCANDINAVICA, 2009, 53 (06) :742-748

[27] Downregulation of angiotensin-converting enzyme by tumor necrosis factor-α and interleukin-1β in cultured human endothelial cells [J].

Saijonmaa, O ;

Nyman, T ;

Fyhrquist, F .

JOURNAL OF VASCULAR RESEARCH, 2001, 38 (04) :370-378

[28] GLOMERULAR TUMOR-NECROSIS-FACTOR AND INTERLEUKIN-1 DURING ACUTE AMINONUCLEOSIDE NEPHROSIS - AN IMMUNOHISTOCHEMICAL STUDY [J].

DIAMOND, JR ;

PESEK, I .

LABORATORY INVESTIGATION, 1991, 64 (01) :21-28

[29] Longitudinal study of inflammatory factors in serum, cerebrospinal fluid, and brain tissue in Alzheimer disease:: Interleukin-1β, interleukin-6, interleukin-1 receptor antagonist, tumor necrosis factor-α, the soluble tumor necrosis factor receptors I and III, and α1-antichymotrypsin [J].

Lanzrein, AS ;

Johnston, CM ;

Perry, VH ;

Jobst, KA ;

King, EM ;

Smith, AD .

ALZHEIMER DISEASE & ASSOCIATED DISORDERS, 1998, 12 (03) :215-227

[30] Acute effect of two exercise intensity programs on interleukin-6, interleukin-1 beta and tumour necrosis factor-α in female futsalists [J].

Zar, A. ;

Ahmadi, E. ;

Amani, D. ;

Ramsbottom, R. .

COMPARATIVE EXERCISE PHYSIOLOGY, 2022, 18 (01) :57-63

← 1 2 3 4 5 →