The role of miRNAs in the diagnosis and treatment of male infertility: a review study

被引：0
作者：
Roya Sinaei
Khosro Jamebozorgi
Hossein Mirshekarpour
Hossein Poormasoumi
Amirhossein Mahdizadeh
Zahra Akbari
Eskandar Taghizadeh
机构：
[1] Islamic Azad University,Department of Genetics, Tehran Medical Sciences
[2] Zabol University of Medical Sciences,Faculty of Medicine
[3] Kerman University of Medical Sciences,Nuclear Medicine of Shafa Hospital
[4] Ahvaz Jundishapur University of Medical Sciences,Department of Medical Genetics, Faculty of Medicine
[5] Ahvaz Jundishapur University of Medical Sciences,Department of Periodontics, School of Dentistry
来源：
Egyptian Journal of Medical Human Genetics | / 24卷
关键词：
MiRNA; Biomarkers; Male infertility; Diagnosis; Therapeutics;
D O I：
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学科分类号：
摘要：
Infertility is a widespread issue that affects over five million couples globally. The cause of this condition can be related to women, men, or both. Male infertility, as a clinical disorder, can be caused by problems in spermatogenesis, testicular development, epididymal, and sperm maturation. Various methods have been proposed to diagnose and treat this disorder, but in some cases, it still remains idiopathic. Nowadays, the investigation of miRNAs is being discussed for the diagnosis and treatment of male infertility. miRNAs are small non-coding RNAs that regulate the expression of many genes after transcription. The aim of this review is to study miRNAs as noninvasive biomarkers for the diagnosis of infertility, as well as proposed treatment strategies and the challenges ahead in these avenues.
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[1]  
Rotimi DE(2023)Therapeutic potential of rutin in male infertility: a mini review J Integr Med 21 130-135
[2]  
Elebiyo TC(2021)European Association of Urology Guidelines on Male Sexual and Reproductive Health: 2021 update on male infertility Eur Urol 80 603-620
[3]  
Ojo OA(2011)Global access to infertility care in developing countries: a case of human rights, equity and social justice Facts Views Vis Obgyn 3 66-257
[4]  
Minhas S(2015)EDC-2: The Endocrine Society's Second Scientific Statement on endocrine-disrupting chemicals Endocr Rev 36 1-150
[5]  
Bettocchi C(2012)National, regional, and global trends in infertility prevalence since 1990: a systematic analysis of 277 health surveys PLoS Med 9 e1001356-11
[6]  
Boeri L(2022)Estimating the effects of policies on infertility prevalence worldwide BMC Public Health 22 1-89
[7]  
Capogrosso P(2013)Human rights to in vitro fertilization Int J Gynecol Obstet 123 86-1545
[8]  
Carvalho J(2017)Proposals for paraphilic disorders in the international classification of diseases and related health problems, eleventh revision (ICD-11) Arch Sex Behav 46 1529-1236
[9]  
Cilesiz NC(2010)A public health focus on infertility prevention, detection, and management Fertil Steril 93 16-150
[10]  
Ombelet W(2021)MicroRNA: a potential diagnosis for male infertility Mini Rev Med Chem 21 1226-8
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