Lyotropic phase behaviour of dilute, aqueous hen lysozyme amyloid fibril dispersions

被引:0
作者
Christian Müller
Olle Inganäs
机构
[1] Linköpings Universitet,Biomolecular and Organic Electronics, Department of Physics, Chemistry and Biology (IFM)
[2] Institut de Ciència de Materials de Barcelona (ICMAB-CSIC),undefined
[3] Esfera UAB,undefined
来源
Journal of Materials Science | 2011年 / 46卷
关键词
Lysozyme; Amyloid Fibril; Amyloid Formation; Initial Protein Concentration; Lyotropic Phase;
D O I
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中图分类号
学科分类号
摘要
We explore the lyotropic phase behaviour of dilute, aqueous amyloid fibril dispersions from hen egg white lysozyme with respect to protein and acid concentration in order to establish preparation protocols that provide homogeneous nematic phases. Such ordered dispersions are demonstrated to facilitate alignment of amyloid nanofibrils in thin solid films, which are utilised to structure conjugated (poly)electrolytes. In addition, the occurrence of ordered phases is found to be in good qualitative agreement with phase equilibria predicted for dispersions of rod-like particles.
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页码:3687 / 3692
页数:5
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