Revisiting Imiquimod for Treatment of Folliculotropic Mycosis Fungoides: A Case Report and Review of the Literature

被引：0
作者：
Doaa Shalabi
Nish Vadalia
Neda Nikbakht
机构：
[1] Thomas Jefferson University,Department of Dermatology and Cutaneous Biology
来源：
Dermatology and Therapy | 2019年 / 9卷
关键词：
Folliculotropic mycosis fungoides; Imiquimod; Toll-like receptor 7 agonist;
D O I：
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学科分类号：
摘要：
Folliculotropic mycosis fungoides (FMF) is an aggressive variant of mycosis fungoides (MF) characterized by infiltration of the hair follicle epithelium by neoplastic T cells. FMF demonstrates poor response rates to standard skin-directed therapies such as phototherapy and topical corticosteroids. Imiquimod, an immunomodulatory agent that stimulates the antitumor immune response, has been used successfully in treatment of early-stage MF. We report a 21-year-old patient with unilesional FMF who achieved clinical remission with imiquimod application. This case highlights a potential for use of imiquimod as a treatment option for patients with FMF and limited skin involvement.
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页码：807 / 814
页数：7
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