The antitumor components from marine-derived bacterium Streptoverticillium luteoverticillatum 11014 II

被引：2
|
作者：
Li D. [1 ]
Zhu T. [1 ]
Fang Y. [1 ]
Liu H. [1 ]
Gu Q. [1 ]
Zhu W. [1 ]
机构：
[1] Key Laboratory of Marine Drug Chinese Ministry of Education, Institute of Marine Drug and Food, Ocean University of China
来源：
Journal of Ocean University of China | 2007年 / 6卷 / 2期
基金：
中国国家自然科学基金;
关键词：
Antitumor activity; Marine-derived bacterium; Streptoverticillium luteoverticillatum;
D O I：
10.1007/s11802-007-0193-4
中图分类号：
学科分类号：
摘要：
Eight known compounds were isolated from a marine-derived bacterium Streptoverticillium luteoverticillatum 11014 using bioassay-guided fractionations. Their structures were identified by spectral analysis as bis (4-hydroxybenzyl) ether (1), p-hydroxyphenylethyl alcohol (2), N-(4-hydroxyphenethyl) acetamide (3), indole-3 carboxylic acid methyl ester (4), dibenzol[b,e] [1,4]dioxine (5), thymine (6), cytosine deoxyribonucleoside (7) and 2, 3-butanediol (8). These compounds were evaluated for their cytot oxic activities against K562 cell line with the SRB method for the first time. Compounds 2 and 4 showed cytotoxicities with IC50 values of 101.1 and 165.3 μmolL-1, respectively. All compounds were isolated from S. luteoverticillatum 11014 for the first time. © Science Press 2007.
引用
收藏
页码：193 / 195
页数：2
相关论文
共 50 条
  • [1] The Antitumor Components from Marine-derived Bacterium Streptoverticillium luteoverticillatum 11014 Ⅱ
    LI Dehai
    Journal of Ocean University of China, 2007, (02) : 193 - 195
  • [2] Four butenolides are novel cytotoxic compounds isolated from the marine-derived bacterium, Streptoverticillium luteoverticillatum 11014
    Li, De-Hai
    Zhu, Tian-Jiao
    Liu, Hong-Bing
    Fang, Yu-Chun
    Gu, Qian-Qun
    Zhu, We-Ming
    ARCHIVES OF PHARMACAL RESEARCH, 2006, 29 (08) : 624 - 626
  • [3] Four butenolides are novel cytotoxic compounds isolated from the marine-derived bacterium,Streptoverticillium luteoverticillatum 11014
    De -Hai Li
    Tian -Jiao Zhu
    Hong -Bing Liu
    Yu -Chun Fang
    Qian -Qun Gu
    Wei -Ming Zhu
    Archives of Pharmacal Research, 2006, 29 : 624 - 626
  • [4] Ieodoglucomides A and B from a Marine-Derived Bacterium Bacillus licheniformis
    Tareq, Fakir Shahidullah
    Kim, Ji Hye
    Lee, Min Ah
    Lee, Hyi-Seung
    Lee, Yeon-Ju
    Lee, Jong Seok
    Shin, Hee Jae
    ORGANIC LETTERS, 2012, 14 (06) : 1464 - 1467
  • [5] In vitro production of marine-derived antitumor compounds
    Pomponi, SA
    Willoughby, R
    Wright, AE
    Pecorella, C
    Sennett, SH
    Lopez, J
    Samples, G
    NEW DEVELOPMENTS IN MARINE BIOTECHNOLOGY, 1998, : 73 - 76
  • [6] Piperazimycins:: Cytotoxic hexadepsipeptides from a marine-derived bacterium of the genus Streptomyces
    Miller, Eric D.
    Kauffman, Christopher A.
    Jensen, Paul R.
    Fenical, William
    JOURNAL OF ORGANIC CHEMISTRY, 2007, 72 (02): : 323 - 330
  • [7] A new cyclic peptide from a marine-derived bacterium of the genus Nocardiopsis
    Shin, J
    Seo, Y
    Lee, HS
    Rho, JR
    Mo, SJ
    JOURNAL OF NATURAL PRODUCTS, 2003, 66 (06): : 883 - 884
  • [8] Kailuin F, a new cyclic acyldepsipeptide from a marine-derived bacterium
    Raju, Ritesh
    Kawabata, Kazutaka
    Nishijima, Miyuki
    Aalbersberg, William G. L.
    TETRAHEDRON LETTERS, 2012, 53 (51) : 6905 - 6907
  • [9] Thalassosamide, a Siderophore Discovered from the Marine-Derived Bacterium Thalassospira profundimaris
    Zhang, Fan
    Barns, Kenneth
    Hoffmann, F. Michael
    Braun, Doug R.
    Andes, David R.
    Bugni, Tim S.
    JOURNAL OF NATURAL PRODUCTS, 2017, 80 (09): : 2551 - 2555
  • [10] Amicoumacins from the marine-derived bacterium Bacillus sp with the inhibition of NO production
    Bai, Jian
    Liu, Dong
    Yu, Siwang
    Proksch, Peter
    Lin, Wenhan
    TETRAHEDRON LETTERS, 2014, 55 (45) : 6286 - 6291
12345