A novel pancreatic tumour and stellate cell 3D co-culture spheroid model

[21] Radhakrishnan P(2012)Fibroblast EXT1-levels influence tumor cell proliferation and migration in composite spheroids PLoS One 7 e41334-501

[22] Olive KP(2014)Tumor cell-targeted delivery of nanoconjugated oligonucleotides in composite spheroids Nucleic Acid Ther 24 413-196

[23] Jacobetz MA(2001)A heterologous 3-D coculture model of breast tumor cells and fibroblasts to study tumor-associated fibroblast differentiation Exp Cell Res 266 74-332

[24] Davidson CJ(2014)Spheroid formation and invasion capacity are differentially influenced by co-cultures of fibroblast and macrophage cells in breast cancer Mol Biol Rep 41 2885-142

[25] Gopinathan A(2011)Modeling colon adenocarcinomas in vitro a 3D co-culture system induces cancer-relevant pathways upon tumor cell and stromal fibroblast interaction Am J Pathol 179 487-452

[26] McIntyre D(2015)Co-culture of 3D tumor spheroids with fibroblasts as a model for epithelial-mesenchymal transition in vitro Exp Cell Res 335 187-1291

[27] Honess D(2013)A multicellular 3D heterospheroid model of liver tumor and stromal cells in collagen gel for anti-cancer drug testing Biochem Biophys Res Commun 433 327-483

[28] Rhim AD(2016)Generation of an in vitro 3D PDAC stroma rich spheroid model Biomaterials 108 129-140

[29] Oberstein PE(2003)A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform Virchows Arch 442 444-516

[30] Thomas DH(2005)Immortalization of pancreatic stellate cells as an in vitro model of pancreatic fibrosis: deactivation is induced by matrigel and N-acetylcysteine Lab Invest 85 1276-77

[21] Radhakrishnan P(2012)Fibroblast EXT1-levels influence tumor cell proliferation and migration in composite spheroids PLoS One 7 e41334-501

[22] Olive KP(2014)Tumor cell-targeted delivery of nanoconjugated oligonucleotides in composite spheroids Nucleic Acid Ther 24 413-196

[23] Jacobetz MA(2001)A heterologous 3-D coculture model of breast tumor cells and fibroblasts to study tumor-associated fibroblast differentiation Exp Cell Res 266 74-332

[24] Davidson CJ(2014)Spheroid formation and invasion capacity are differentially influenced by co-cultures of fibroblast and macrophage cells in breast cancer Mol Biol Rep 41 2885-142

[25] Gopinathan A(2011)Modeling colon adenocarcinomas in vitro a 3D co-culture system induces cancer-relevant pathways upon tumor cell and stromal fibroblast interaction Am J Pathol 179 487-452

[26] McIntyre D(2015)Co-culture of 3D tumor spheroids with fibroblasts as a model for epithelial-mesenchymal transition in vitro Exp Cell Res 335 187-1291

[27] Honess D(2013)A multicellular 3D heterospheroid model of liver tumor and stromal cells in collagen gel for anti-cancer drug testing Biochem Biophys Res Commun 433 327-483

[28] Rhim AD(2016)Generation of an in vitro 3D PDAC stroma rich spheroid model Biomaterials 108 129-140

[29] Oberstein PE(2003)A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform Virchows Arch 442 444-516

[30] Thomas DH(2005)Immortalization of pancreatic stellate cells as an in vitro model of pancreatic fibrosis: deactivation is induced by matrigel and N-acetylcysteine Lab Invest 85 1276-77