A novel pancreatic tumour and stellate cell 3D co-culture spheroid model

[1] Bray F(2018)Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 68 394-424

[2] Ferlay J(2019)A systematic assessment of statistics, risk factors, and underlying features involved in pancreatic cancer Cancer Epidemiol 58 104-110

[3] Soerjomataram I(2019)Targeting pancreatic stellate cells in Cancer Trends Cancer 5 128-142

[4] Siegel RL(2001)Transforming growth factor-beta1 induces desmoplasia in an experimental model of human pancreatic carcinoma Cancer Res 61 550-555

[5] Torre LA(2020)Pancreatic stellate cells: the key orchestrator of the pancreatic tumor microenvironment Adv Exp Med Biol 1234 57-70

[6] Jemal A(2009)Inhibition of hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer Science 324 1457-1461

[7] Aier I(2014)Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma Cancer Cell 25 735-747

[8] Semwal R(2015)Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas Cancer with reduced survival Cancer Cell 28 831-833

[9] Sharma A(2014)Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy Cell 159 80-93

[10] Varadwaj PK(2018)Reshaping the tumor Stroma for treatment of pancreatic Cancer Gastroenterology 154 820-838

[1] Bray F(2018)Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 68 394-424

[2] Ferlay J(2019)A systematic assessment of statistics, risk factors, and underlying features involved in pancreatic cancer Cancer Epidemiol 58 104-110

[3] Soerjomataram I(2019)Targeting pancreatic stellate cells in Cancer Trends Cancer 5 128-142

[4] Siegel RL(2001)Transforming growth factor-beta1 induces desmoplasia in an experimental model of human pancreatic carcinoma Cancer Res 61 550-555

[5] Torre LA(2020)Pancreatic stellate cells: the key orchestrator of the pancreatic tumor microenvironment Adv Exp Med Biol 1234 57-70

[6] Jemal A(2009)Inhibition of hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer Science 324 1457-1461

[7] Aier I(2014)Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma Cancer Cell 25 735-747

[8] Semwal R(2015)Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas Cancer with reduced survival Cancer Cell 28 831-833

[9] Sharma A(2014)Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy Cell 159 80-93

[10] Varadwaj PK(2018)Reshaping the tumor Stroma for treatment of pancreatic Cancer Gastroenterology 154 820-838