Incidence of diabetes retinopathy and determinants of time to diabetes retinopathy among diabetes patients at Tikur Anbessa Hospital, Ethiopia: A retrospective follow up study

被引:21
作者
Azeze T.K. [1 ]
Sisay M.M. [2 ]
Zeleke E.G. [2 ]
机构
[1] Ethiopian Postal Service Enterprise, Addis Ababa
[2] Department of Epidemiology and Biostatistics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar
关键词
Complication of diabetes mellitus; Determinants; Diabetes retinopathy; Ethiopia; Incidence;
D O I
10.1186/s13104-018-3660-7
中图分类号
学科分类号
摘要
Objective: Data regarding diabetes retinopathy and associated factors are currently lacking in Ethiopia. The study aims to determine the incidence and determinants of time to diabetes retinopathy among diabetes mellitus patients at Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia. Results: The incidence of diabetes retinopathy is a rapidly growing burden of disease in Ethiopia. The incidence rate of diabetes retinopathy was 2.65 (95% CI 2. 54, 4.05) per 1000 person-years observation. Moreover, 70 (18.57%, 95% CI 14.63, 22.5) DM patients developed diabetes retinopathy. The median time was 74.07 months (with IQR 53.60, 89.88). Male sex (AHR = 1.94, 95% CI = 1.10, 3.39), type 2 DM (AHR = 4.01, 95% CI = 1.34, 12.00), creatinine (AHR = 2.59, 95% CI = 1.91, 3.52), borderline triglyceride (AHR = 2.87, 95% CI 1.33, 6.21) and high triglyceride levels (AHR = 2.59, 95% CI = 1.31, 4.97) were positively correlated factors to diabetes retinopathy occurrence. Multisectoral, population-based approaches are needed to reduce type 2 DM complications. © 2018 The Author(s).
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共 47 条
[1]  
Global Report on Diabetes, (2016)
[2]  
Bourne R.R.A., Et al., Causes of vision loss worldwide, 1990-2010: A systematic analysis, Lancet Glob Health., (2013)
[3]  
Klein B.E., Overview of epidemiologic studies of diabetic retinopathy, Ophthal Epidemiol, 14, 4, pp. 179-183, (2007)
[4]  
Hall V., Thomsen R.W., Henriksen O., Lohse N., Diabetes in sub Saharan Africa 1999-2011: Epidemiology and public health implications. A systematic review, BMC Public Health., 11, 1, (2011)
[5]  
Worku D., Hamza L., Woldemichael K., Patterns of diabetic complications at Jimma university specialized hospital, Southwest Ethiopia, Ethiop J Health Sci., 20, 1, pp. 33-39, (2010)
[6]  
Alemu S., Dessie A., Tsegaw A., Patterson C.C., Parry E.H., Phillips D.I., Trimble E.R., Retinopathy in type 1 diabetes mellitus: Major differences between rural and urban dwellers in northwest Ethiopia, Diabetes Res Clin Pract., 109, 1, pp. 191-198, (2015)
[7]  
Martino E., Et al., Incidence of retinal complications in a cohort of newly diagnosed diabetic patients, PLoS ONE., 9, 6, (2014)
[8]  
Klein R., Klein K.B., Moss S.E., Cruickshanks K.J., The Wisconsin Epidemiologic Study of Diabetic Retinopathy XV: The long-term incidence of macular edema, Am Acad Ophthalmol, 102, 1, pp. 7-16, (1995)
[9]  
Klein R., Knudston M.D., Lee K.E., Gangnon R., Klein B.E., The Wisconsin epidemiologic study of diabetic retinopathy XXII: The twenty-five-year progression of retinopathy with type 1 diabetes, Ophthalmology., 115, 11, pp. 1859-1868, (2008)
[10]  
Thomas R.L., Dunstan F., Luzio S.D., Chowdury S.R., Hale S.L., North R.V., Gibbins R.L., Owens D.R., Incidence of diabetic retinopathy in people with type 2 diabetes mellitus attending the Diabetic Retinopathy Screening Service for Wales: Retrospective analysis, BMJ., 344, (2011)