Multifunctional wearable devices for diagnosis and therapy of movement disorders

被引：0

作者：

Son D. ^{[1
,2
]}

Lee J. ^{[1
,2
]}

Qiao S. ^{[3
]}

Ghaffari R. ^{[4
]}

Kim J. ^{[1
,2
]}

Lee J.E. ^{[1
,2
]}

Song C. ^{[1
,2
]}

Kim S.J. ^{[1
,2
]}

Lee D.J. ^{[1
,2
]}

Jun S.W. ^{[1
,2
]}

Yang S. ^{[3
]}

Park M. ^{[1
,2
]}

Shin J. ^{[1
,2
]}

Do K. ^{[1
,2
]}

Lee M. ^{[1
,2
]}

Kang K. ^{[1
,2
]}

Hwang C.S. ^{[5
]}

Lu N. ^{[1
,2
]}

Hyeon T. ^{[1
,2
]}

Kim D.-H. ^{[1
,2
]}

机构：

[1] Center for Nanoparticle Research, Institute for Basic Science (IBS)

[2] School of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University

[3] Department of Aerospace Engineering and Engineering Mechanics, Texas Materials Institute, University of Texas at Austin, Austin, TX 78712

[4] MC10 Inc., Cambridge, MA 02140

[5] Department of Materials Science and Engineering, Inter-university Semiconductor Research Center, Seoul National University

来源：

Nature Nanotechnology | 2014年 / 9卷 / 5期

基金：

新加坡国家研究基金会;

关键词：

D O I：

10.1038/nnano.2014.38

中图分类号：

学科分类号：

摘要：

Wearable systems that monitor muscle activity, store data and deliver feedback therapy are the next frontier in personalized medicine and healthcare. However, technical challenges, such as the fabrication of high-performance, energy-efficient sensors and memory modules that are in intimate mechanical contact with soft tissues, in conjunction with controlled delivery of therapeutic agents, limit the wide-scale adoption of such systems. Here, we describe materials, mechanics and designs for multifunctional, wearable-on-the-skin systems that address these challenges via monolithic integration of nanomembranes fabricated with a top-down approach, nanoparticles assembled by bottom-up methods, and stretchable electronics on a tissue-like polymeric substrate. Representative examples of such systems include physiological sensors, non-volatile memory and drug-release actuators. Quantitative analyses of the electronics, mechanics, heat-transfer and drug-diffusion characteristics validate the operation of individual components, thereby enabling system-level multifunctionalities. © 2014 Macmillan Publishers Limited. All rights reserved.

引用

页码：397 / 404

页数：7

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