The role of miRNAs in the development of prostate cancer

被引：0
|
作者：
G. B. Kunsbaeva
I. R. Gilyazova
V. N. Pavlov
E. K. Khusnutdinova
机构：
[1] Bashkir State University,Department of Genetics
[2] Russian Academy of Sciences,Institute of Biochemistry and Genetics, Ufa Scientific Center
[3] Bashkir State Medical University,Department of Urology
来源：
Russian Journal of Genetics | 2015年 / 51卷
关键词：
Prostate Cancer; Androgen Receptor; Chronic Lympho Cytic Leukemia; Prostate Cancer Cell; Gleason Score;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
MicroRNAs (miRNAs) act as key post-transcriptional regulators of gene expression. This review examines current advances in the study of the role of miRNAs in cancer, including prostate cancer. Issues devoted to the nomenclature, biogenesis, the role of miRNAs as oncogenes and tumor suppressors, and their role in the diagnosis, treatment, and prognosis of prostate cancer are discussed. Assessment of the role of miRNAs in the development of prostate cancer will promote early diagnosis and will be important for the development of new approaches to the disease treatment.
引用
收藏
页码：627 / 641
页数：14
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